HitPredict

Interactor 1: LSM3 (P62310)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSM3

Interactor 2: LSM10 (Q969L4)
U7 snRNA-associated Sm-like protein LSm10
Gene: LSM10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	16189514, 15231747, 33961781, 19060904
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 102 Hs			1 123
+	Dm
		1213197 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9VKW8_DROME (18-113): 1.21e-35: 121: 25.77
+	Hs
		912211 LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00		LSM4_HUMAN (18-90): 3.27e-32: 111: 27.03
+	Hs
		912140 LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Hs
		912142 LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00		SMD3_HUMAN (18-114): 3.72e-31: 108: 20.62
+	Hs
		912205 LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00		LSM2_HUMAN (19-102): 7.92e-31: 107: 25.58
+	Dm
		1213199 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9VTW6_DROME (19-106): 1.33e-31: 109: 25.56
+	Hs
		911791 LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00		RUXF_HUMAN (20-83): 3.98e-26: 95: 26.56
+	Hs
		912139 LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00		LSM6_HUMAN (6-82): 3.34e-25: 92.3: 27.27
+	Dm
		1367655 SMD2_DROME (13-95): 3.12e-27: 97.8: 30.23		Q9VKW8_DROME (18-113): 1.21e-35: 121: 25.77
+	At
		1323437 Q9FI15_ARATH (23-99): 4.19e-27: 101: 25.00		SMD1B_ARATH (17-110): 7.82e-34: 115: 30.85
+	At
		1352883 Q9SUN5_ARATH (23-99): 1.97e-24: 94.3: 25.00		SMD1B_ARATH (17-110): 7.82e-34: 115: 30.85
+	Hs
		928049 RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81		LSM4_HUMAN (18-90): 3.27e-32: 111: 27.03
+	Dm
		218370 SMD2_DROME (13-95): 3.12e-27: 97.8: 30.23		SMD3_DROME (18-113): 4.72e-31: 109: 20.83
+	Hs
		912265 RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Dm
		1367658 SMD2_DROME (13-95): 3.12e-27: 97.8: 30.23		SMD1_DROME (17-108): 4.32e-31: 108: 26.09
+	Hs
		912611 RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81		SMD3_HUMAN (18-114): 3.72e-31: 108: 20.62
+	Hs
		928046 RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81		LSM2_HUMAN (19-102): 7.92e-31: 107: 25.58
+	Sp
		293324 LSM3_SCHPO (9-98): 2.02e-30: 105: 57.78		LSM2_SCHPO (19-100): 3.05e-25: 93.1: 25.00
+	Hs
		911801 RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81		RUXF_HUMAN (20-83): 3.98e-26: 95: 26.56
+	Hs
		912220 RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81		LSM6_HUMAN (6-82): 3.34e-25: 92.3: 27.27