HitPredict

Interactor 1: LSM6 (P62312)
U6 snRNA-associated Sm-like protein LSm6
Gene: LSM6

Interactor 2: LSM10 (Q969L4)
U7 snRNA-associated Sm-like protein LSm10
Gene: LSM10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 80 Hs			1 123
+	Hs
		911921 RUXF_HUMAN (5-74): 6.03e-31: 105: 48.57		LSM10_HUMAN (1-123): 5.17e-50: 156: 100.00
+	Zm
		38861 A0A1D6MPT6_MAIZE (8-80): 7.96e-34: 115: 29.73		A0A1D6MPT6_MAIZE (18-106): 1.68e-36: 124: 25.56
+	Hs
		912405 LSM4_HUMAN (8-80): 5.81e-33: 112: 27.03		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Dm
		1369696 Q9VKW8_DROME (8-80): 4.87e-33: 112: 27.03		Q9VTW6_DROME (19-106): 1.33e-31: 109: 25.56
+	Dm
		1369699 Q9W2P5_DROME (4-80): 4.69e-29: 100: 85.71		Q9VKW8_DROME (18-113): 1.21e-35: 121: 25.77
+	Hs
		912217 LSM6_HUMAN (1-80): 3.99e-33: 110: 100.00		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Hs
		912765 LSM4_HUMAN (8-80): 5.81e-33: 112: 27.03		SMD3_HUMAN (18-114): 3.72e-31: 108: 20.62
+	Hs
		1377523 LSM4_HUMAN (8-80): 5.81e-33: 112: 27.03		LSM2_HUMAN (19-102): 7.92e-31: 107: 25.58
+	Hs
		912257 LSM6_HUMAN (1-80): 3.99e-33: 110: 100.00		LSM2_HUMAN (19-102): 7.92e-31: 107: 25.58
+	Hs
		911793 RUXF_HUMAN (5-74): 6.03e-31: 105: 48.57		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Dm
		218361 RUXF_DROME (2-74): 1.97e-30: 104: 43.84		SMD3_DROME (18-113): 4.72e-31: 109: 20.83
+	Hs
		911795 RUXF_HUMAN (5-74): 6.03e-31: 105: 48.57		SMD3_HUMAN (18-114): 3.72e-31: 108: 20.62
+	Hs
		912002 RUXF_HUMAN (5-74): 6.03e-31: 105: 48.57		LSM2_HUMAN (19-102): 7.92e-31: 107: 25.58
+	Hs
		912008 LSM4_HUMAN (8-80): 5.81e-33: 112: 27.03		RUXF_HUMAN (20-83): 3.98e-26: 95: 26.56
+	At
		1352880 RUXF_ARATH (1-74): 2.77e-31: 106: 45.95		RUXF_ARATH (20-96): 8.07e-28: 99.3: 23.08
+	Hs
		911792 LSM6_HUMAN (1-80): 3.99e-33: 110: 100.00		RUXF_HUMAN (20-83): 3.98e-26: 95: 26.56
+	Hs
		912260 LSM4_HUMAN (8-80): 5.81e-33: 112: 27.03		LSM6_HUMAN (6-82): 3.34e-25: 92.3: 27.27