Protein: PDRG1
p53 and DNA damage-regulated protein 1

Gene: PDRG1
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q9NUG6

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0016272 - prefoldin complex
GO:0050821 - protein stabilization
GO:0051082 - unfolded protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1449786

PFD2
Prefoldin subunit 2

5

1

High-throughput

0.919

High

1449784

UXT
Protein UXT

4

1

Small-scale

0.895

High

316449

RMP
Unconventional prefoldin RPB5 interactor 1

4

2

Small-scale

0.873

High

182191

PFD6
Prefoldin subunit 6

3

1

High-throughput

0.847

High

1447141

PFD4
Prefoldin subunit 4

3

0

High-throughput

0.811

High

963378

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.770

High

786877

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

8

2

High-throughput

0.750

High

967996

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

6

2

Small-scale

0.737

High

261881

PFD1
Prefoldin subunit 1

2

0

High-throughput

0.736

High

1435178

RPAP3
RNA polymerase II-associated protein 3

6

0

Small-scale

0.699

High

1449789

RUVB1
RuvB-like 1

4

2

High-throughput

0.697

High

1449788

RUVB2
RuvB-like 2

4

2

High-throughput

0.691

High

1449780

PIHD1
PIH1 domain-containing protein 1

5

0

Small-scale

0.684

High

621983

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

1

High-throughput

0.662

High

1313058

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

3

0

High-throughput

0.628

High

945597

FBXW4
F-box/WD repeat-containing protein 4

3

1

High-throughput

0.609

High

1144183

TEBP
Prostaglandin E synthase 3

2

0

High-throughput

0.602

High

1187351

DC4L1
DDB1- and CUL4-associated factor 4-like protein 1

2

1

High-throughput

0.601

High

1447085

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

3

2

High-throughput

0.593

High

1449790

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

2

High-throughput

0.593

High

1404679

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.586

High

647451

SCP2
Sterol carrier protein 2

2

0

High-throughput

0.585

High

984304

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

2

0

High-throughput

0.585

High

1292813

SKAP1
Src kinase-associated phosphoprotein 1

2

0

High-throughput

0.585

High

1395149

DCAF5
DDB1- and CUL4-associated factor 5

2

0

High-throughput

0.585

High

1398615

DAA10
Dynein axonemal assembly factor 10

2

1

High-throughput

0.584

High

340042

RPA1
DNA-directed RNA polymerase I subunit RPA1

2

2

High-throughput

0.558

High

723109

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

2

High-throughput

0.558

High

1363094

DDB2
DNA damage-binding protein 2

2

1

High-throughput

0.558

High

968459

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.536

High

912243

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

1

High-throughput

0.521

High

976159

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

1

High-throughput

0.521

High

251260

RNBP6
Ran-binding protein 6

1

0

High-throughput

0.513

High

461972

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.513

High

1148878

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.513

High

1250427

KSR2
Kinase suppressor of Ras 2

1

0

High-throughput

0.513

High

1315861

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.513

High

1382541

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

1449785

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

1

0

High-throughput

0.513

High

1407245

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.493

High

1332553

DC4L2
DDB1- and CUL4-associated factor 4-like protein 2

1

1

High-throughput

0.489

High

165097

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

2

High-throughput

0.479

High

180413

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.479

High

997155

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.479

High

1259530

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.479

High

1449779

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

132328

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

184327

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

341688

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.458

High

376000

RASK
GTPase KRas

1

0

High-throughput

0.458

High

1156871

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1364618

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

621764

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

667474

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.437

High

787795

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

2

High-throughput

0.437

High

1217621

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.437

High

1399364

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

2

High-throughput

0.437

High

1437313

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.437

High

1449783

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

2

High-throughput

0.437

High

1449791

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

1

High-throughput

0.437

High

58947

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

516875

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.407

High

1434857

ASB7
Ankyrin repeat and SOCS box protein 7

2

0

High-throughput

0.328

High

430651

RPC4
DNA-directed RNA polymerase III subunit RPC4

2

0

High-throughput

0.318

High

912134

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

0

High-throughput

0.318

High

923547

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

0

High-throughput

0.318

High

983715

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.318

High

1449777

RPC5
DNA-directed RNA polymerase III subunit RPC5

2

0

High-throughput

0.318

High

1347469

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

1449787

GPN3
GPN-loop GTPase 3

2

0

High-throughput

0.313

High

1232026

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

2

0

High-throughput

0.305

High

272762

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

High-throughput

0.279

Low

571523

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.279

Low

914068

SPSY
Spermine synthase

1

0

High-throughput

0.279

Low

1120362

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.279

Low

1187757

KR133
Keratin-associated protein 13-3

1

0

High-throughput

0.279

Low

1287305

WDR86
WD repeat-containing protein 86

1

0

High-throughput

0.279

Low

1339345

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.279

Low

1446171

PAR6A
Partitioning defective 6 homolog alpha

1

0

High-throughput

0.279

Low

1449781

ASB6
Ankyrin repeat and SOCS box protein 6

1

0

High-throughput

0.279

Low

191121

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.249

Low

192865

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.249

Low

287486

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.249

Low

290172

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.249

Low

694013

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

959067

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

1108405

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.249

Low

1138682

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.249

Low

1148688

SYCP1
Synaptonemal complex protein 1

1

0

High-throughput

0.249

Low

1163668

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

0

High-throughput

0.249

Low

1241813

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.249

Low

1309901

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

1428644

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1446517

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

1449778

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

1449782

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

506034

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low

1225125

NSN5C
Putative methyltransferase NSUN5C

1

0

High-throughput

0.232

Low

1381602

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

0

High-throughput

0.232

Low

1445930

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025