HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: MRCKA (Q5VT25)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 1732
+	Hs
		148636 RAB1A_HUMAN (1-174): 6.74e-67: 204: 18.99		CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43
+	Hs
		149274 RAB1B_HUMAN (10-174): 1.3e-66: 203: 19.41		CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43
+	Hs
		148603 ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54		CTRO_HUMAN (4-1044): 3.09e-128: 447: 24.43
+	Dm
		897448 ARF1_DROME (2-175): 1.01e-64: 197: 70.12		AKT1_DROME (13-399): 4.98e-127: 413: 28.96
+	Hs
		913176 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		TNIK_HUMAN (53-905): 4.35e-97: 346: 15.60
+	Hs
		254465 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ROCK2_HUMAN (373-1052): 1.4e-22: 108: 12.07
+	Hs
		912888 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ROCK1_HUMAN (361-1052): 1.07e-20: 101: 11.28