HitPredict

Interactor 1: E5RI47 (E5RI47)
MAGUK p55 scaffold protein 2
Gene: MPP2

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	L27~L27, PDZ~PDZ
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 197
+	Hs
		1050418 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		1050415 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		1346107 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		91352 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		1334778 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158282 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		91342 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		158304 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		159277 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		159269 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158254 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Mm
		1143555 MPP2_MOUSE (1-189): 9.84e-76: 238: 94.36		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		1021489 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		159203 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		159110 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		159207 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90
+	Hs
		91344 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		159190 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		159200 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		159249 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42