HitPredict

Interactor 1: ABI2 (P62484)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Interactor 2: EPS8 (Q08509)
Epidermal growth factor receptor kinase substrate 8
Gene: EPS8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19564905
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 446 Mm			1 821
+	Mm
		995948 ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24		EPS8_MOUSE (1-821): 0: 975: 100.00
+	Hs
		1020381 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		EPS8_HUMAN (1-821): 0: 971: 89.05
+	Hs
		1224645 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		ES8L2_HUMAN (34-798): 0: 700: 39.97
+	Hs
		1224620 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		ES8L1_HUMAN (34-810): 0: 681: 35.47
+	Hs
		1255835 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		ES8L1_HUMAN (34-810): 0: 681: 35.47
+	Ce
		105690 Q10929_CAEEL (1-441): 1.05e-77: 251: 33.26		G5ED33_CAEEL (62-812): 0: 561: 26.54
+	Hs
		802871 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		CRKL_HUMAN (506-703): 2.12e-39: 150: 17.96
+	Hs
		802656 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		CRK_HUMAN (394-701): 8.81e-39: 148: 11.00
+	Hs
		433413 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		YES_HUMAN (449-593): 5.21e-31: 130: 20.00
+	Hs
		412258 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		FYN_HUMAN (455-593): 1.72e-30: 128: 16.31
+	Hs
		1224619 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		ES8L3_HUMAN (586-783): 7.4e-30: 127: 21.18
+	Hs
		3146 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		A0A0S2Z4E4_HUMAN (531-737): 7.27e-39: 146: 17.87
+	Mm
		223016 ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24		NCK2_MOUSE (487-715): 9.71e-24: 106: 11.16
+	Hs
		557737 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		NCK1_HUMAN (487-737): 7.13e-22: 100: 9.73
+	Hs
		3136 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		A0A0S2Z4D7_HUMAN (531-673): 6.14e-33: 126: 20.98
+	Hs
		209108 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		NCK2_HUMAN (534-620): 7.79e-14: 76.1: 23.33
+	Hs
		557806 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		NCK1_HUMAN (487-737): 7.13e-22: 100: 9.73
+	Hs
		209180 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		NCK2_HUMAN (534-620): 7.79e-14: 76.1: 23.33
+	Hs
		1045423 SPTN1_HUMAN (2-443): 1.67e-52: 192: 13.23		ITSN1_HUMAN (401-760): 8.92e-24: 110: 9.39
+	Sp
		999951 CDC15_SCHPO (126-441): 8.79e-39: 151: 18.35		MYO1_SCHPO (416-599): 7.24e-31: 132: 14.05