HitPredict

Interactor 1: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Interactor 2: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb2_7~S1, RNA_pol_Rpb2_7~SHS2_Rpb7-N
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 1133
+	Hs
		1347030 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPC2_HUMAN (1-1133): 0: 1714: 100.00
+	Hs
		87263 RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00		C9J2Y9_HUMAN (14-1127): 0: 1476: 37.52
+	Hs
		676855 RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00		RPB2_HUMAN (14-1127): 0: 1475: 37.52
+	Dm
		627154 Q9VTL6_DROME (1-157): 1.99e-51: 166: 17.79		RPC2_DROME (14-1131): 0: 1504: 68.81
+	Hs
		677063 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPB2_HUMAN (14-1127): 0: 1475: 37.52
+	Sc
		606613 RPC8_YEAST (1-158): 1.07e-49: 160: 19.39		RPC2_YEAST (12-1130): 0: 1471: 62.84
+	Sp
		145817 RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42		RPB2_SCHPO (19-1131): 0: 1388: 34.93
+	Sc
		440009 RPB7_YEAST (1-171): 4.45e-63: 193: 42.78		RPB2_YEAST (13-1130): 0: 1382: 36.70
+	Pf
		1257374 Q8U439_PYRFU (1-170): 1.73e-47: 154: 20.23		Q8U0M3_PYRFU (22-1130): 0: 1318: 36.92
+	Hs
		913957 RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00		RPA2_HUMAN (36-1128): 0: 1159: 29.59
+	Hs
		1334528 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPA2_HUMAN (36-1128): 0: 1159: 29.59