HitPredict

Interactor 1: RB11A (P62491)
Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (YL8)
Gene: RAB11A

Interactor 2: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0070062 - extracellular exosome GO:0072659 - protein localization to plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 337
+	Hs
		884496 RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20		NHRF2_HUMAN (1-337): 6.02e-79: 246: 100.00
+	Hs
		153904 RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00		NHRF1_HUMAN (2-337): 3.61e-70: 224: 48.87
+	Hs
		153902 RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20		NHRF1_HUMAN (2-337): 3.61e-70: 224: 48.87
+	Hs
		914039 RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00		DLG1_HUMAN (87-235): 1.55e-13: 73.5: 17.31
+	Hs
		914066 RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00		SCRIB_HUMAN (4-185): 3.63e-13: 72.7: 18.37
+	Hs
		884480 RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20		DLG1_HUMAN (87-235): 1.55e-13: 73.5: 17.31