HitPredict

Interactor 1: ERR3 (P62508)
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)
Gene: ESRRG

Interactor 2: PROX1 (Q92786)
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)
Gene: PROX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

The method score is based on:

Property	Details
Experiments	33961781, 15604093
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	458
Hs

1	737

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024