HitPredict

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 27880917, 35271311, 34349018, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos
Common GO terms GO:0000159 - protein phosphatase type 2A complex
GO:0000278 - mitotic cell cycle
GO:0000775 - chromosome, centromeric region
GO:0000922 - spindle pole
GO:0004722 - protein serine/threonine phosphatase activity
and 10 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 309
Hs

1 309
+ Sc
+ Hs
+ Hs
+ Sc
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024