Protein: PTPRU
Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)

Gene: PTPRU
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q92729

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0006470 - protein dephosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1044874

AAMP
Angio-associated migratory cell protein

3

0

High-throughput

0.816

High

1069953

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

2

18

High-throughput

0.811

High

1269186

CLC2D
C-type lectin domain family 2 member D

2

8

High-throughput

0.811

High

1269167

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

17

Small-scale

0.699

High

383910

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.698

High

354737

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

3

High-throughput

0.691

High

560086

CTLA4
Cytotoxic T-lymphocyte protein 4

1

1

High-throughput

0.691

High

570359

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

4

High-throughput

0.691

High

644614

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

7

High-throughput

0.691

High

964681

IL5RA
Interleukin-5 receptor subunit alpha

1

20

High-throughput

0.691

High

1103651

HFE
Hereditary hemochromatosis protein

1

6

High-throughput

0.691

High

1269175

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

1269187

BTNL2
Butyrophilin-like protein 2

1

9

High-throughput

0.691

High

1083586

SGCA
Alpha-sarcoglycan

3

2

High-throughput

0.667

High

158964

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.656

High

717247

CTNB1
Catenin beta-1

3

20

Small-scale

0.650

High

338787

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.647

High

702788

CADH5
Cadherin-5

2

20

High-throughput

0.628

High

1269198

PCDGD
Protocadherin gamma-B1

2

15

High-throughput

0.628

High

533027

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.618

High

1100775

CL12B
C-type lectin domain family 12 member B

1

5

High-throughput

0.618

High

499281

KIT
Mast/stem cell growth factor receptor Kit

1

15

Small-scale

0.618

High

876460

AFAD
Afadin

1

10

High-throughput

0.618

High

129411

GOLI4
Golgi integral membrane protein 4

3

4

High-throughput

0.609

High

1262511

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

6

High-throughput

0.574

High

1269171

TAFA4
Chemokine-like protein TAFA-4

2

1

High-throughput

0.574

High

161128

CLGN
Calmegin

2

8

High-throughput

0.558

High

61703

CDHR4
Cadherin-related family member 4

1

19

High-throughput

0.536

High

875881

MFAP4
Microfibril-associated glycoprotein 4

1

4

High-throughput

0.536

High

1217152

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.536

High

1236747

PCD20
Protocadherin-20

1

17

High-throughput

0.536

High

1269188

FBX2
F-box only protein 2

1

8

High-throughput

0.536

High

1269189

PCDGG
Protocadherin gamma-B4

1

16

High-throughput

0.536

High

1269195

PCDB7
Protocadherin beta-7

1

15

High-throughput

0.536

High

1269196

PCDB3
Protocadherin beta-3

1

15

High-throughput

0.536

High

1269197

PCDGM
Protocadherin gamma-C5

1

15

High-throughput

0.536

High

1234472

MACOI
Macoilin

2

1

High-throughput

0.533

High

1269168

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

1269170

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.513

High

1269193

TMM98
Transmembrane protein 98

1

0

High-throughput

0.513

High

617793

OMGP
Oligodendrocyte-myelin glycoprotein

1

6

Small-scale

0.501

High

724556

IRS1
Insulin receptor substrate 1

1

6

Small-scale

0.501

High

217397

VEGFD
Vascular endothelial growth factor D

1

2

High-throughput

0.489

High

305276

NXPH3
Neurexophilin-3

1

1

High-throughput

0.489

High

319613

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.489

High

362546

C1QB
Complement C1q subcomponent subunit B

1

3

High-throughput

0.489

High

1223982

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1232365

TAFA2
Chemokine-like protein TAFA-2

1

1

High-throughput

0.489

High

1265341

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

1

High-throughput

0.489

High

1269177

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.489

High

1269179

FBX6
F-box only protein 6

1

8

High-throughput

0.489

High

1269180

CAH10
Carbonic anhydrase-related protein 10

1

5

High-throughput

0.489

High

1269181

CBLN4
Cerebellin-4

1

2

High-throughput

0.489

High

1269184

DNJB9
DnaJ homolog subfamily B member 9

1

9

High-throughput

0.489

High

899914

OSTN
Osteocrin

1

0

Small-scale

0.480

High

387217

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

716740

CTNA1
Catenin alpha-1

1

1

High-throughput

0.479

High

763064

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.479

High

820994

PRC2A
Protein PRRC2A

1

1

High-throughput

0.479

High

1022686

RHG05
Rho GTPase-activating protein 5

1

1

High-throughput

0.479

High

1047787

CKAP5
Cytoskeleton-associated protein 5

1

9

High-throughput

0.479

High

1048635

DSG2
Desmoglein-2

1

20

High-throughput

0.479

High

1067777

PDIA6
Protein disulfide-isomerase A6

1

13

High-throughput

0.479

High

1127662

PRC2B
Protein PRRC2B

1

3

High-throughput

0.479

High

1132219

NHSL1
NHS-like protein 1

1

5

High-throughput

0.479

High

1164572

NHS
Actin remodeling regulator NHS

1

5

High-throughput

0.479

High

1269169

ASTRA
Protein Aster-A

1

1

High-throughput

0.479

High

1269174

ACE2
Angiotensin-converting enzyme 2

1

2

Small-scale

0.479

High

1269176

UN45A
Protein unc-45 homolog A

1

2

High-throughput

0.479

High

734478

ARL2
ADP-ribosylation factor-like protein 2

1

5

High-throughput

0.470

High

240117

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

1047187

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

122060

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

6

High-throughput

0.437

High

163077

XPO1
Exportin-1

1

13

High-throughput

0.437

High

423314

PDIA1
Protein disulfide-isomerase

1

13

High-throughput

0.437

High

531930

PDIA4
Protein disulfide-isomerase A4

1

13

High-throughput

0.437

High

653680

CALR
Calreticulin

1

8

High-throughput

0.437

High

654626

CALX
Calnexin

1

8

High-throughput

0.437

High

671887

PDIA3
Protein disulfide-isomerase A3

1

13

High-throughput

0.437

High

874554

XPO2
Exportin-2

1

11

High-throughput

0.437

High

875174

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.437

High

944351

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.437

High

972796

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

3

High-throughput

0.437

High

1058500

GANAB
Neutral alpha-glucosidase AB

1

4

High-throughput

0.437

High

1069032

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.437

High

1072702

UBE3C
Ubiquitin-protein ligase E3C

1

4

High-throughput

0.437

High

1101516

KIF7
Kinesin-like protein KIF7

1

2

High-throughput

0.437

High

1189546

MON2
Protein MON2 homolog

1

2

High-throughput

0.437

High

1220443

DJC10
DnaJ homolog subfamily C member 10

1

19

High-throughput

0.437

High

1256552

PO210
Nuclear pore membrane glycoprotein 210

1

2

High-throughput

0.437

High

1269172

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

4

High-throughput

0.437

High

1269173

FUT8
Alpha-(1,6)-fucosyltransferase

1

2

High-throughput

0.437

High

1269182

ABI2
Abl interactor 2

1

9

High-throughput

0.437

High

1269183

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

3

High-throughput

0.437

High

1269185

DJB11
DnaJ homolog subfamily B member 11

1

1

High-throughput

0.437

High

1269190

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

2

High-throughput

0.437

High

1269191

DJC16
DnaJ homolog subfamily C member 16

1

17

High-throughput

0.437

High

1269192

MAN1
Inner nuclear membrane protein Man1

1

1

High-throughput

0.437

High

328158

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.328

High

211389

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

1204301

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

1251361

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.279

Low

51106

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.249

Low

231135

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.249

Low

649645

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

1183655

TM10C
tRNA methyltransferase 10 homolog C

1

0

High-throughput

0.249

Low

1269178

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1269194

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.249

Low

230642

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024