HitPredict

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: P2R3B (Q9Y5P8)
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit)
Gene: PPP2R3B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

Property	Details
Experiments	26186194, 26496610, 27880917, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_7~Metallophos
Common GO terms	GO:0000159 - protein phosphatase type 2A complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0006470 - protein dephosphorylation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 575
+	Hs
		931057 PP2AA_HUMAN (1-309): 0: 533: 97.41		P2R3B_HUMAN (1-575): 0: 827: 100.00
+	Mm
		102664 PP2AA_MOUSE (1-309): 0: 532: 97.41		G3X9E8_MOUSE (77-535): 0: 622: 59.57
+	Hs
		930814 PP2AA_HUMAN (1-309): 0: 533: 97.41		P2R3A_HUMAN (119-535): 0: 609: 64.46
+	Hs
		930950 PP2AA_HUMAN (1-309): 0: 533: 97.41		P2R3C_HUMAN (104-501): 2.64e-128: 385: 19.76
+	Hs
		915251 PP2AB_HUMAN (1-309): 0: 532: 100.00		P2R3C_HUMAN (104-501): 2.64e-128: 385: 19.76
+	Ce
		108327 PP2A_CAEEL (3-309): 0: 523: 89.58		P2R31_CAEEL (112-485): 1.52e-62: 213: 17.35