HitPredict

Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 793
+	Hs
		984599 ACTBL_HUMAN (4-377): 0: 712: 87.97		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		724859 ACTBL_HUMAN (4-377): 0: 712: 87.97		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		891710 ACTB_HUMAN (4-377): 0: 598: 94.12		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		929831 ACTG_HUMAN (4-377): 0: 598: 94.39		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		891935 ACTB_HUMAN (4-377): 0: 598: 94.12		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		929952 ACTG_HUMAN (4-377): 0: 598: 94.39		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		933030 ACTS_HUMAN (1-377): 0: 598: 97.88		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		725136 ACTC_HUMAN (1-377): 0: 598: 98.41		MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63
+	Rn
		892236 ACTB_RAT (4-377): 0: 598: 94.12		MYH10_RAT (55-785): 3.7e-26: 117: 10.67
+	Mm
		892205 ACTB_MOUSE (4-377): 0: 598: 94.12		MYH9_MOUSE (2-638): 2.4e-23: 108: 10.87
+	Hs
		724738 ACTB_HUMAN (4-377): 0: 598: 94.12		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		724762 ACTG_HUMAN (4-377): 0: 598: 94.39		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		724766 ACTC_HUMAN (1-377): 0: 598: 98.41		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		724767 ACTS_HUMAN (1-377): 0: 598: 97.88		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Rn
		892228 ACTB_RAT (4-377): 0: 598: 94.12		MYH9_RAT (2-603): 1.07e-21: 103: 10.66
+	Hs
		929869 ACTG_HUMAN (4-377): 0: 598: 94.39		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Rn
		92841 ACTB_RAT (4-377): 0: 598: 94.12		CTRO_RAT (81-718): 1.96e-16: 86.4: 9.75
+	Hs
		148662 ACTC_HUMAN (1-377): 0: 598: 98.41		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		891686 ACTB_HUMAN (4-377): 0: 598: 94.12		MAP1A_HUMAN (212-642): 6.08e-13: 75: 18.04
+	Hs
		930015 ACTG_HUMAN (4-377): 0: 598: 94.39		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38