HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0006886 - intracellular protein transport GO:0019901 - protein kinase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1675
+	Hs
		925199 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		900383 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		545326 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		436257 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		950928 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		892321 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		893908 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		564482 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		120392 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Dm
		669565 RAC1_DROME (1-196): 1.58e-77: 231: 53.06		CLH_DROME (1-1663): 0: 2911: 80.17