HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: MAGI1 (Q96QZ7)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)
Gene: MAGI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1491
+	Hs
		925536 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MAGI1_HUMAN (1-1491): 0: 756: 100.00
+	Hs
		925236 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		900421 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Hs
		915636 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTN13_HUMAN (227-1419): 7.85e-57: 220: 10.78
+	Mm
		925797 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DLG4_MOUSE (14-110): 4.36e-17: 89.1: 19.61
+	Hs
		925239 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		125349 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		915880 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG3_HUMAN (16-556): 6.49e-16: 85.6: 12.05
+	Hs
		900424 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		915639 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG1_HUMAN (14-110): 1.24e-15: 84.8: 19.61
+	Hs
		125308 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		125330 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		WWP2_HUMAN (215-434): 9.36e-15: 82: 29.39
+	Hs
		925463 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		900726 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		915860 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PARD3_HUMAN (362-806): 5.29e-13: 76.6: 16.74
+	Hs
		900710 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		915848 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		INADL_HUMAN (14-131): 7.48e-13: 76: 14.75
+	Hs
		925273 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		900463 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26
+	Hs
		915673 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SCRIB_HUMAN (838-1232): 4.22e-09: 63.5: 23.26