HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PANX1 (Q96RD7)
Pannexin-1 (PANX1) [Cleaved into: Caspase-activated pannexin-1 (Caspase-activated PANX1)]
Gene: PANX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 426
+	Hs
		925537 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		900821 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		545569 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		436470 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		951247 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		892546 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		894334 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		PANX1_HUMAN (1-426): 0: 642: 100.00
+	Hs
		564650 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		PANX1_HUMAN (1-426): 0: 642: 100.00