HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: DAPLE (Q9P219)
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
Gene: CCDC88C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 2028
+	Hs
		900999 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DAPLE_HUMAN (1-2028): 0: 630: 100.00
+	Hs
		925322 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		900534 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		915716 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		545414 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		436338 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		951040 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Mm
		916115 RHOB_MOUSE (1-196): 7.52e-78: 232: 100.00		MAP1A_MOUSE (1287-2020): 9.65e-76: 283: 14.47
+	Mm
		823530 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		CTRO_MOUSE (140-948): 1.4e-46: 187: 17.23
+	Mm
		823539 RHOA_MOUSE (1-196): 3.27e-78: 233: 83.16		CTRO_MOUSE (140-948): 1.4e-46: 187: 17.23
+	Mm
		823529 CDC42_MOUSE (1-196): 1.35e-74: 224: 49.49		CTRO_MOUSE (140-948): 1.4e-46: 187: 17.23
+	Hs
		725138 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		148653 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		148608 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		148632 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		148297 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		724757 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		724776 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		915702 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ITSN1_HUMAN (60-424): 6.95e-14: 79.9: 11.52
+	Hs
		915600 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MAP1A_HUMAN (228-541): 1.95e-10: 68.5: 12.54