Protein: NU153
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)

Gene: NU153, NUP153
Organism: Homo sapiens
Interactions: 214
UniProt ID: P49790

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

890294

RAN
GTP-binding nuclear protein Ran

6

20

Small-scale

0.950

High

890417

G3BP2
Ras GTPase-activating protein-binding protein 2

2

15

High-throughput

0.789

High

890332

LARP7
La-related protein 7

2

18

High-throughput

0.754

High

890415

NUP50
Nuclear pore complex protein Nup50

9

19

Small-scale

0.752

High

890320

IMB1
Importin subunit beta-1

9

20

Small-scale

0.752

High

890410

NXF1
Nuclear RNA export factor 1

7

19

Small-scale

0.742

High

890282

IMA1
Importin subunit alpha-1

5

20

High-throughput

0.720

High

552774

TPR
Nucleoprotein TPR

4

20

Small-scale

0.703

High

385558

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

5

20

High-throughput

0.702

High

890292

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

4

9

High-throughput

0.699

High

786451

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

9

High-throughput

0.694

High

431026

LA
Lupus La protein

1

12

High-throughput

0.691

High

890376

PSPC1
Paraspeckle component 1

1

16

High-throughput

0.691

High

890364

NUP43
Nucleoporin Nup43

4

20

High-throughput

0.686

High

890283

IMA5
Importin subunit alpha-5

3

20

High-throughput

0.675

High

890331

TSR1
Pre-rRNA-processing protein TSR1 homolog

3

2

High-throughput

0.675

High

890397

NXF2
Nuclear RNA export factor 2

3

19

Small-scale

0.670

High

890402

SENP2
Sentrin-specific protease 2

3

8

Small-scale

0.664

High

890382

TNPO1
Transportin-1

3

20

Small-scale

0.662

High

890366

NUP35
Nucleoporin NUP35

3

8

High-throughput

0.656

High

890394

NUP85
Nuclear pore complex protein Nup85

3

10

High-throughput

0.656

High

890373

NU133
Nuclear pore complex protein Nup133

3

9

Small-scale

0.650

High

798849

BRCA1
Breast cancer type 1 susceptibility protein

3

17

Small-scale

0.631

High

142505

IMA3
Importin subunit alpha-3

2

20

High-throughput

0.628

High

253601

IMA7
Importin subunit alpha-7

2

20

High-throughput

0.628

High

890304

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

15

High-throughput

0.628

High

890362

SR1IP
Protein SREK1IP1

2

1

High-throughput

0.628

High

890393

KIFC1
Kinesin-like protein KIFC1

2

12

High-throughput

0.628

High

890310

GRSF1
G-rich sequence factor 1

1

20

Small-scale

0.621

High

890290

NTF2
Nuclear transport factor 2

2

18

Small-scale

0.619

High

754762

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

371478

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.611

High

634355

LMNB1
Lamin-B1

2

20

High-throughput

0.611

High

775503

NU214
Nuclear pore complex protein Nup214

2

20

Small-scale

0.611

High

890279

RBP2
E3 SUMO-protein ligase RanBP2

2

18

Small-scale

0.611

High

890285

NUP98
Nuclear pore complex protein Nup98-Nup96

2

17

Small-scale

0.611

High

890287

NU107
Nuclear pore complex protein Nup107

2

12

High-throughput

0.611

High

890309

NU160
Nuclear pore complex protein Nup160

2

7

High-throughput

0.611

High

890316

CUL3
Cullin-3

2

17

High-throughput

0.611

High

890391

IER2
Immediate early response gene 2 protein

2

2

High-throughput

0.611

High

890395

NUSAP
Nucleolar and spindle-associated protein 1

2

2

High-throughput

0.611

High

890387

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

8

High-throughput

0.601

High

172585

XPO1
Exportin-1

2

20

Small-scale

0.595

High

890407

TYDP1
Tyrosyl-DNA phosphodiesterase 1

2

0

High-throughput

0.585

High

128860

MEN1
Menin

2

5

High-throughput

0.584

High

227430

SPOP
Speckle-type POZ protein

2

7

High-throughput

0.584

High

259630

BRD4
Bromodomain-containing protein 4

2

19

High-throughput

0.584

High

291254

NU155
Nuclear pore complex protein Nup155

2

14

High-throughput

0.584

High

830346

CCNF
Cyclin-F

2

5

High-throughput

0.584

High

890293

H4
Histone H4

2

9

High-throughput

0.584

High

890284

NCBP2
Nuclear cap-binding protein subunit 2

1

16

High-throughput

0.575

High

890357

SLX4
Structure-specific endonuclease subunit SLX4

2

17

High-throughput

0.571

High

789075

NUP62
Nuclear pore glycoprotein p62

1

20

Small-scale

0.561

High

890297

DYLT1
Dynein light chain Tctex-type 1

1

2

Small-scale

0.561

High

890335

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

7

Small-scale

0.552

High

890278

NU153
Nuclear pore complex protein Nup153

1

18

Small-scale

0.543

High

668530

APC
Adenomatous polyposis coli protein

1

20

High-throughput

0.541

High

771059

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

1

High-throughput

0.541

High

138653

IMA4
Importin subunit alpha-4

1

20

High-throughput

0.536

High

161596

RGPD8
RANBP2-like and GRIP domain-containing protein 8

1

16

High-throughput

0.536

High

164548

TNPO2
Transportin-2

1

20

High-throughput

0.536

High

166129

AIM2
Interferon-inducible protein AIM2

1

8

High-throughput

0.536

High

179034

IMA6
Importin subunit alpha-6

1

20

High-throughput

0.536

High

186192

PPM1D
Protein phosphatase 1D

1

5

High-throughput

0.536

High

192564

NUP42
Nucleoporin NUP42

1

1

High-throughput

0.536

High

334718

IPO7
Importin-7

1

20

High-throughput

0.536

High

616271

RCC1
Regulator of chromosome condensation

1

13

High-throughput

0.536

High

662542

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

8

High-throughput

0.536

High

755668

MCM4
DNA replication licensing factor MCM4

1

14

High-throughput

0.536

High

764547

CTNB1
Catenin beta-1

1

20

High-throughput

0.536

High

849305

RANG
Ran-specific GTPase-activating protein

1

19

High-throughput

0.536

High

854607

RAGP1
Ran GTPase-activating protein 1

1

9

High-throughput

0.536

High

890281

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

12

High-throughput

0.536

High

890289

SUMO2
Small ubiquitin-related modifier 2

1

15

High-throughput

0.536

High

890296

SUMO1
Small ubiquitin-related modifier 1

1

15

High-throughput

0.536

High

890298

UBC9
SUMO-conjugating enzyme UBC9

1

18

High-throughput

0.536

High

890300

RAE1L
mRNA export factor RAE1

1

20

High-throughput

0.536

High

890305

CENPC
Centromere protein C

1

8

High-throughput

0.536

High

890307

CTSL2
CTD small phosphatase-like protein 2

1

6

High-throughput

0.536

High

890315

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.536

High

890321

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

15

High-throughput

0.536

High

890322

NUMA1
Nuclear mitotic apparatus protein 1

1

17

High-throughput

0.536

High

890325

MARE1
Microtubule-associated protein RP/EB family member 1

1

8

High-throughput

0.536

High

890329

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

7

High-throughput

0.536

High

890334

GLE1
mRNA export factor GLE1

1

15

High-throughput

0.536

High

890336

NU188
Nucleoporin NUP188

1

3

High-throughput

0.536

High

890339

CDCA2
Cell division cycle-associated protein 2

1

2

High-throughput

0.536

High

890340

TM214
Transmembrane protein 214

1

1

High-throughput

0.536

High

890344

PHF5A
PHD finger-like domain-containing protein 5A

1

1

High-throughput

0.536

High

890355

KLHL7
Kelch-like protein 7

1

2

High-throughput

0.536

High

890358

NUP93
Nuclear pore complex protein Nup93

1

6

High-throughput

0.536

High

890365

NUP37
Nucleoporin Nup37

1

20

High-throughput

0.536

High

890367

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.536

High

890370

PO210
Nuclear pore membrane glycoprotein 210

1

2

High-throughput

0.536

High

890379

NU205
Nuclear pore complex protein Nup205

1

11

High-throughput

0.536

High

890383

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

13

High-throughput

0.536

High

890385

SEH1
Nucleoporin SEH1

1

20

High-throughput

0.536

High

890386

P121A
Nuclear envelope pore membrane protein POM 121

1

19

High-throughput

0.536

High

890388

TM209
Transmembrane protein 209

1

1

High-throughput

0.536

High

890389

NUP88
Nuclear pore complex protein Nup88

1

4

High-throughput

0.536

High

890404

DDX21
Nucleolar RNA helicase 2

1

12

High-throughput

0.536

High

890406

AAAS
Aladin

1

16

High-throughput

0.536

High

890408

NSMA3
Sphingomyelin phosphodiesterase 4

1

1

High-throughput

0.536

High

890409

SENP1
Sentrin-specific protease 1

1

8

High-throughput

0.536

High

890420

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

13

High-throughput

0.536

High

890421

NOP58
Nucleolar protein 58

1

4

High-throughput

0.536

High

890323

HAPR1
HUWE1-associated protein modifying stress responses 1

2

3

Small-scale

0.533

High

710794

EPHB2
Ephrin type-B receptor 2

1

5

Small-scale

0.527

High

890328

MK14
Mitogen-activated protein kinase 14

1

12

Small-scale

0.527

High

890374

DEP1B
DEP domain-containing protein 1B

2

5

High-throughput

0.521

High

683407

IKBA
NF-kappa-B inhibitor alpha

1

19

Small-scale

0.515

High

890392

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.513

High

890400

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.513

High

133981

IPO5
Importin-5

1

20

Small-scale

0.501

High

691679

MK03
Mitogen-activated protein kinase 3

1

11

Small-scale

0.501

High

703499

MK01
Mitogen-activated protein kinase 1

1

11

Small-scale

0.501

High

890303

SMAD3
Mothers against decapentaplegic homolog 3

1

12

Small-scale

0.501

High

890412

XPO7
Exportin-7

1

20

Small-scale

0.501

High

395702

ESR1
Estrogen receptor

1

20

High-throughput

0.500

High

96968

NPIB6
Nuclear pore complex-interacting protein family member B6

1

4

High-throughput

0.489

High

890302

HTRA4
Serine protease HTRA4

1

4

High-throughput

0.489

High

890384

HDA11
Histone deacetylase 11

1

17

High-throughput

0.489

High

890418

DICER
Endoribonuclease Dicer

1

11

Small-scale

0.484

High

157099

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

194058

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

222830

PRC1
Protein regulator of cytokinesis 1

1

13

High-throughput

0.479

High

271989

OBSL1
Obscurin-like protein 1

1

13

High-throughput

0.479

High

342795

HERC2
E3 ubiquitin-protein ligase HERC2

1

12

High-throughput

0.479

High

362976

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.479

High

557950

XRCC6
X-ray repair cross-complementing protein 6

1

8

High-throughput

0.479

High

588204

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

606431

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

607552

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

9

High-throughput

0.479

High

642721

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

6

High-throughput

0.479

High

694929

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

702900

DPOD1
DNA polymerase delta catalytic subunit

1

4

High-throughput

0.479

High

731084

STIP1
Stress-induced-phosphoprotein 1

1

14

High-throughput

0.479

High

767698

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

832878

CETN2
Centrin-2

1

2

Small-scale

0.479

High

838019

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

10

Small-scale

0.479

High

854797

RECQ1
ATP-dependent DNA helicase Q1

1

14

High-throughput

0.479

High

878778

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

19

High-throughput

0.479

High

890280

EMD
Emerin

1

5

High-throughput

0.479

High

890286

FOXA1
Hepatocyte nuclear factor 3-alpha

1

14

High-throughput

0.479

High

890288

SC61B
Protein transport protein Sec61 subunit beta

1

5

High-throughput

0.479

High

890291

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

890295

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

19

High-throughput

0.479

High

890299

ACTC
Actin, alpha cardiac muscle 1

1

9

High-throughput

0.479

High

890301

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.479

High

890306

TF65
Transcription factor p65

1

16

High-throughput

0.479

High

890311

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

10

High-throughput

0.479

High

890312

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

2

High-throughput

0.479

High

890313

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.479

High

890314

BIRC3
Baculoviral IAP repeat-containing protein 3

1

12

High-throughput

0.479

High

890317

CUL4B
Cullin-4B

1

17

High-throughput

0.479

High

890319

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.479

High

890324

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

890327

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

1

High-throughput

0.479

High

890330

IF16
Gamma-interferon-inducible protein 16

1

8

High-throughput

0.479

High

890338

RNF43
E3 ubiquitin-protein ligase RNF43

1

8

High-throughput

0.479

High

890343

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

890345

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

15

High-throughput

0.479

High

890347

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

11

High-throughput

0.479

High

890348

SLN11
Schlafen family member 11

1

3

High-throughput

0.479

High

890349

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

7

High-throughput

0.479

High

890350

NAA40
N-alpha-acetyltransferase 40

1

6

High-throughput

0.479

High

890353

CUL9
Cullin-9

1

18

Small-scale

0.479

High

890356

SMC5
Structural maintenance of chromosomes protein 5

1

11

High-throughput

0.479

High

890360

SIR6
NAD-dependent protein deacylase sirtuin-6

1

16

High-throughput

0.479

High

890363

SCAI
Protein SCAI

1

1

Small-scale

0.479

High

890369

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

890377

TOPB1
DNA topoisomerase 2-binding protein 1

1

19

High-throughput

0.479

High

890378

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

890380

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

890381

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

8

High-throughput

0.479

High

890390

B9D2
B9 domain-containing protein 2

1

2

High-throughput

0.479

High

890396

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

890399

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

890401

XPO5
Exportin-5

1

20

Small-scale

0.479

High

890403

ANLN
Anillin

1

5

High-throughput

0.479

High

890405

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

16

High-throughput

0.479

High

890411

ZRAN1
Ubiquitin thioesterase ZRANB1

1

18

High-throughput

0.479

High

890413

HERC5
E3 ISG15--protein ligase HERC5

1

5

Small-scale

0.479

High

890414

FBW1B
F-box/WD repeat-containing protein 11

1

15

High-throughput

0.479

High

890416

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.479

High

890419

FBW1A
F-box/WD repeat-containing protein 1A

1

18

High-throughput

0.479

High

889376

CLK1
Dual specificity protein kinase CLK1

1

15

High-throughput

0.457

High

62471

S35F4
Solute carrier family 35 member F4

1

1

High-throughput

0.445

High

68011

P121C
Nuclear envelope pore membrane protein POM 121C

1

20

High-throughput

0.445

High

96917

E9PF10
Nucleoporin 155

1

14

High-throughput

0.445

High

116915

J3KMX2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

1

7

High-throughput

0.445

High

354601

PAK4
Serine/threonine-protein kinase PAK 4

1

8

High-throughput

0.445

High

890308

NCBP1
Nuclear cap-binding protein subunit 1

1

2

High-throughput

0.445

High

890318

ASPP2
Apoptosis-stimulating of p53 protein 2

1

20

Small-scale

0.445

High

890326

UT2
Urea transporter 2

1

1

High-throughput

0.445

High

890351

S2611
Sodium-independent sulfate anion transporter

1

1

High-throughput

0.445

High

890354

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

5

High-throughput

0.445

High

890359

STAG2
Cohesin subunit SA-2

1

3

Small-scale

0.445

High

890361

S35G3
Solute carrier family 35 member G3

1

1

High-throughput

0.445

High

890372

IASPP
RelA-associated inhibitor

1

18

Small-scale

0.445

High

890375

STAG1
Cohesin subunit SA-1

1

3

Small-scale

0.445

High

76100

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

20

High-throughput

0.437

High

293379

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

890333

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

5

High-throughput

0.437

High

890337

OTUD1
OTU domain-containing protein 1

1

10

High-throughput

0.437

High

890341

RHDF2
Inactive rhomboid protein 2

1

6

High-throughput

0.437

High

890342

LMBRL
Protein LMBR1L

1

4

High-throughput

0.437

High

890368

RHBL4
Rhomboid-related protein 4

1

6

High-throughput

0.437

High

890398

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

890371

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

886634

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.408

High

890346

RIC3
Protein RIC-3

1

1

High-throughput

0.407

High

890352

PPR3B
Protein phosphatase 1 regulatory subunit 3B

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025