HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1085
+	Hs
		925735 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A4_HUMAN (1-1085): 0: 1180: 100.00
+	Hs
		901055 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A4_HUMAN (1-1085): 0: 1180: 100.00
+	Hs
		916053 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A6_HUMAN (7-1085): 0: 1111: 76.53
+	Hs
		925769 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		916106 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		873903 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		873898 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		873902 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		854874 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTR2_HUMAN (161-603): 2.22e-92: 311: 15.54
+	Hs
		854869 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTR2_HUMAN (161-603): 2.22e-92: 311: 15.54
+	Hs
		854873 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTR2_HUMAN (161-603): 2.22e-92: 311: 15.54
+	Hs
		676533 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		676530 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		676532 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		925480 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		YLAT2_HUMAN (162-661): 2.93e-81: 276: 11.91
+	Hs
		900749 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		YLAT2_HUMAN (162-661): 2.93e-81: 276: 11.91
+	Hs
		915871 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		YLAT2_HUMAN (162-661): 2.93e-81: 276: 11.91
+	Hs
		925205 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		LAT1_HUMAN (162-687): 1.61e-79: 271: 13.65
+	Hs
		900388 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		LAT1_HUMAN (162-687): 1.61e-79: 271: 13.65
+	Hs
		915614 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		LAT1_HUMAN (162-687): 1.61e-79: 271: 13.65