HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: FARP1 (Q9Y4F1)
FERM, ARHGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (FERM, RhoGEF and pleckstrin domain-containing protein 1) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2)
Gene: FARP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras, PH~Ras, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1045
+	Hs
		925760 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		901085 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		545718 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		FARP1_HUMAN (1-1045): 0: 848: 100.00
+	Hs
		925613 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41L1_HUMAN (20-550): 6.05e-122: 396: 29.16
+	Hs
		925637 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		900899 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		E41L1_HUMAN (20-550): 6.05e-122: 396: 29.16
+	Hs
		915972 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		E41L1_HUMAN (20-550): 6.05e-122: 396: 29.16
+	Hs
		545616 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		E41L1_HUMAN (20-550): 6.05e-122: 396: 29.16
+	Hs
		900931 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		915991 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		545630 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		E41L5_HUMAN (7-551): 1.15e-122: 394: 26.72
+	Hs
		925748 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41L3_HUMAN (35-538): 1.5e-115: 384: 30.87
+	Hs
		204646 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		E41L2_HUMAN (3-549): 7.69e-117: 386: 29.58
+	Mm
		250712 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		E41L2_MOUSE (3-549): 7.29e-115: 380: 29.95
+	Hs
		901065 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		E41L3_HUMAN (35-538): 1.5e-115: 384: 30.87
+	Hs
		925608 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41LB_HUMAN (26-547): 2.8e-110: 365: 25.52
+	Hs
		547002 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		546995 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		EZRI_HUMAN (37-558): 4.42e-103: 337: 20.07
+	Hs
		719697 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25
+	Hs
		545234 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		RADI_HUMAN (37-582): 1.65e-99: 327: 19.25