HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: S12A7 (Q9Y666)
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)
Gene: SLC12A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1083
+	Hs
		925769 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		901099 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		925735 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		901055 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		916077 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		916053 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A6_HUMAN (14-1083): 0: 1102: 69.47
+	Hs
		873903 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		873898 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		873902 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		854874 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		854869 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		854873 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		545280 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		676533 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		676530 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		676532 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		545221 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35
+	Hs
		925480 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		YLAT2_HUMAN (159-652): 6.01e-78: 267: 12.48
+	Hs
		900749 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		YLAT2_HUMAN (159-652): 6.01e-78: 267: 12.48
+	Hs
		915871 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		YLAT2_HUMAN (159-652): 6.01e-78: 267: 12.48