Protein: NKX25
Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E)

Gene: NKX25, Nkx2-5
Organism: Mus musculus
Interactions: 13
UniProt ID: P42582

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

840131

TBX5
T-box transcription factor TBX5

2

20

Small-scale

0.768

High

840130

TBX1
T-box transcription factor TBX1

1

19

Small-scale

0.618

High

840134

HAND2
Heart- and neural crest derivatives-expressed protein 2

1

8

Small-scale

0.618

High

840136

HAND1
Heart- and neural crest derivatives-expressed protein 1

1

7

Small-scale

0.618

High

840138

MEF2C
Myocyte-specific enhancer factor 2C

1

4

Small-scale

0.618

High

840132

GATA4
Transcription factor GATA-4

2

12

Small-scale

0.601

High

312715

FOXH1
Forkhead box protein H1

2

20

Small-scale

0.586

High

840140

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

Small-scale

0.536

High

840135

JARD2
Protein Jumonji

1

6

Small-scale

0.515

High

840137

NSD2
Histone-lysine N-methyltransferase NSD2

1

20

Small-scale

0.515

High

840133

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.479

High

840139

FBX25
F-box only protein 25

1

1

Small-scale

0.479

High

508970

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

0

Small-scale

0.458

High


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Last updated: 11Aug2025