Interactor 1: DXO (P53063)
Decapping nuclease RAI1 (ScRai1) (EC 3.6.1.-) (NAD-capped RNA hydrolase RAI1) (DeNADding enzyme RAI1) (EC 3.6.1.-) (RAT1-interacting protein)
Gene: RAI1

Interactor 2: XRN2 (Q02792)
5'-3' exoribonuclease 2 (EC 3.1.13.-) (Ribonucleic acid-trafficking protein 1) (p116)
Gene: RAT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 11805826, 23689372, 16554755, 16429126, 25722373, 26638174, 33978753, 37263996, 20826334, 19535338, 12612077, 10805743, 37968396, 39657659
Identification Methods tandem affinity purification, pull down, affinity chromatography technology, enzymatic study, x-ray crystallography, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RAI1~XRN_M, RAI1~XRN_N
Common GO terms GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 387
Sc

1 1006
+ Hs
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025