HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: CBX2 (Q14781)
Chromobox protein homolog 2
Gene: CBX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 532
+	Hs
		123221 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89
+	Hs
		918158 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CDYL_HUMAN (2-297): 1.28e-60: 211: 21.63
+	Hs
		918227 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CDY2_HUMAN (7-297): 3.71e-56: 198: 16.72
+	Hs
		917798 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MPP8_HUMAN (7-397): 6.88e-47: 177: 17.54
+	Mm
		918268 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX6_MOUSE (3-242): 3.88e-43: 160: 31.12
+	Hs
		315996 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX6_HUMAN (3-242): 2.28e-36: 141: 30.29
+	Hs
		917108 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX1_HUMAN (18-153): 1.81e-38: 141: 22.79
+	Mm
		918238 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX1_MOUSE (18-153): 1.81e-38: 141: 22.79
+	Hs
		917958 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX8_HUMAN (3-238): 1.39e-35: 139: 29.39
+	Hs
		917205 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX3_HUMAN (9-152): 1.29e-37: 138: 21.53
+	Hs
		327834 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX7_HUMAN (3-210): 1.4e-35: 135: 27.98
+	Hs
		800335 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBX5_HUMAN (12-152): 1.24e-35: 133: 24.66
+	Mm
		918248 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX5_MOUSE (12-152): 3.66e-35: 132: 25.34
+	Mm
		918259 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		CBX7_MOUSE (3-117): 1.22e-29: 115: 42.24
+	Dm
		639958 H4_DROME (1-103): 4.51e-48: 150: 99.03		PC_DROME (11-158): 2.02e-16: 83: 23.84