Interactor 1: PRP43 (P53131)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 (EC 3.6.4.13) (Helicase JA1)
Gene: PRP43

Interactor 2: PXR1 (P53335)
Protein PXR1 (G-patch nucleolar protein) (PinX1-related protein 1)
Gene: PXR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 25808954, 29054886, 36018804, 39578461, 24823796, 16227579, 37968396, 16429126
Identification Methods pull down, two hybrid, affinity chromatography technology, enzymatic study, x-ray crystallography, tandem affinity purification, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-patch~HA2_N, G-patch~Helicase_C, G-patch~OB_NTP_bind
Common GO terms GO:0005730 - nucleolus
GO:0030490 - maturation of SSU-rRNA
GO:0032040 - small-subunit processome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 767
Sc

1 271
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025