HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 2048
+	Hs
		917635 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD6_HUMAN (42-1218): 5.58e-109: 391: 12.33
+	Hs
		917182 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD3_HUMAN (29-1087): 1.86e-103: 372: 13.16
+	Hs
		229352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA5_HUMAN (4-1049): 3.79e-105: 365: 12.02
+	Hs
		918062 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD7_HUMAN (37-1421): 1.18e-99: 361: 11.19
+	Hs
		917364 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD9_HUMAN (37-1034): 1.46e-96: 351: 12.12
+	Sc
		356350 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CHD1_YEAST (31-1157): 3.76e-102: 364: 12.01
+	Hs
		917965 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88
+	Dm
		950383 H4_DROME (1-103): 4.51e-48: 150: 99.03		ISWI_DROME (4-1010): 2.07e-97: 342: 11.48
+	Sc
		356424 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW1_YEAST (8-1076): 1.54e-97: 344: 11.66
+	Sc
		356528 H4_YEAST (18-103): 6.13e-41: 132: 90.70		MPH1_YEAST (60-729): 9.03e-88: 312: 28.07
+	Hs
		571390 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10
+	Hs
		133964 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70
+	Hs
		917992 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX21_HUMAN (473-672): 2.66e-15: 84.1: 20.48
+	Dm
		950412 H4_DROME (1-103): 4.51e-48: 150: 99.03		DDX3_DROME (278-579): 1.37e-14: 81.8: 18.45