Protein: NSA1
Ribosome biogenesis protein NSA1 (NOP7-associated protein 1)

Gene: NSA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 162
UniProt ID: P53136

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0030687 - preribosome, large subunit precursor
GO:0042273 - ribosomal large subunit biogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917547

NOG1
Nucleolar GTP-binding protein 1

12

1

Small-scale

0.757

High

917538

PESC
Pescadillo homolog

12

2

Small-scale

0.756

High

917557

ERB1
Ribosome biogenesis protein ERB1

10

2

Small-scale

0.753

High

917582

YTM1
Ribosome biogenesis protein YTM1

10

3

Small-scale

0.752

High

917548

HAS1
ATP-dependent RNA helicase HAS1

10

4

Small-scale

0.751

High

805069

RPF1
Ribosome production factor 1

8

2

Small-scale

0.749

High

570081

RL3
Large ribosomal subunit protein uL3

9

1

Small-scale

0.748

High

830144

NOP2
25S rRNA

9

2

Small-scale

0.748

High

917568

NOC3
Nucleolar complex-associated protein 3

8

2

Small-scale

0.747

High

804632

SSF1
Ribosome biogenesis protein SSF1

8

2

Small-scale

0.742

High

782389

RPF2
Ribosome biogenesis protein RPF2

7

1

Small-scale

0.741

High

746647

DRS1
ATP-dependent RNA helicase DRS1

7

1

Small-scale

0.736

High

917588

IF6
Eukaryotic translation initiation factor 6

6

1

Small-scale

0.733

High

917541

NOP15
Ribosome biogenesis protein 15

6

1

Small-scale

0.729

High

803891

CIC1
Proteasome-interacting protein CIC1

6

1

Small-scale

0.726

High

780285

EBP2
rRNA-processing protein EBP2

6

1

Small-scale

0.721

High

917586

DBP10
ATP-dependent RNA helicase DBP10

9

0

Small-scale

0.714

High

793500

MAK5
ATP-dependent RNA helicase MAK5

5

2

Small-scale

0.712

High

917572

BRX1
Ribosome biogenesis protein BRX1

5

9

Small-scale

0.709

High

677220

SPB1
27S pre-rRNA

5

1

Small-scale

0.702

High

682341

SPB4
ATP-dependent rRNA helicase SPB4

5

4

Small-scale

0.702

High

816868

NUG1
Nuclear GTP-binding protein NUG1

5

2

Small-scale

0.702

High

814346

NOC2
Nucleolar complex protein 2

6

0

Small-scale

0.695

High

917555

PUF6
Pumilio homology domain family member 6

6

0

Small-scale

0.695

High

818250

NSA2
Ribosome biogenesis protein NSA2

5

0

Small-scale

0.678

High

534125

MAK16
Protein MAK16

4

2

Small-scale

0.676

High

750111

MRT4
Ribosome assembly factor MRT4

4

2

Small-scale

0.676

High

763095

RRP1
Ribosomal RNA-processing protein 1

4

2

Small-scale

0.676

High

827556

RLP7
Ribosome biogenesis protein RLP7

4

2

Small-scale

0.676

High

917563

DBP9
ATP-dependent RNA helicase DBP9

4

1

Small-scale

0.676

High

917569

RLP24
Ribosome biogenesis protein RLP24

4

1

Small-scale

0.676

High

917585

MAK21
Ribosome biogenesis protein MAK21

4

3

Small-scale

0.676

High

780692

RRP14
Ribosomal RNA-processing protein 14

5

0

Small-scale

0.672

High

633176

MAK11
Protein MAK11

4

1

Small-scale

0.672

High

684788

RL5
Large ribosomal subunit protein uL18

4

0

Small-scale

0.657

High

917580

NIP7
60S ribosome subunit biogenesis protein NIP7

3

1

Small-scale

0.656

High

917564

RRP15
Ribosomal RNA-processing protein 15

4

0

Small-scale

0.648

High

531814

RL4A
Large ribosomal subunit protein uL4A

3

2

Small-scale

0.640

High

917561

FKBP4
FK506-binding protein 4

3

1

Small-scale

0.640

High

917584

SSF2
Ribosome biogenesis protein SSF2

3

2

Small-scale

0.633

High

816778

NOP16
Nucleolar protein 16

3

0

Small-scale

0.613

High

917558

RRP5
rRNA biogenesis protein RRP5

3

0

Small-scale

0.613

High

743255

PP12
Serine/threonine-protein phosphatase PP1-2

2

0

High-throughput

0.602

High

849990

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

0

High-throughput

0.585

High

917570

BUD20
Bud site selection protein 20

2

0

Small-scale

0.585

High

433248

RL17A
Large ribosomal subunit protein uL22A

2

2

Small-scale

0.584

High

689248

RL16B
Large ribosomal subunit protein uL13B

2

2

High-throughput

0.584

High

792151

GBLP
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.584

High

863851

RL17B
Large ribosomal subunit protein uL22B

2

2

Small-scale

0.584

High

917536

NSA1
Ribosome biogenesis protein NSA1

2

1

Small-scale

0.584

High

917542

RCM1
25S rRNA

2

2

High-throughput

0.584

High

917562

JIP5
WD repeat-containing protein JIP5

2

1

High-throughput

0.584

High

433747

RL26A
Large ribosomal subunit protein uL24A

2

0

High-throughput

0.559

High

518081

SSBP1
Single-stranded nucleic acid-binding protein

2

0

Small-scale

0.559

High

917552

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

917583

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.559

High

917567

RIX7
Ribosome biogenesis ATPase RIX7

1

1

Small-scale

0.552

High

432639

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.536

High

722111

XPO1
Exportin-1

1

2

High-throughput

0.536

High

427369

RLA0
Large ribosomal subunit protein uL10

2

2

Small-scale

0.533

High

601085

RL8A
Large ribosomal subunit protein eL8A

2

2

Small-scale

0.533

High

709432

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

917573

DNLI4
DNA ligase 4

1

0

High-throughput

0.513

High

571279

PMS1
DNA mismatch repair protein PMS1

1

0

High-throughput

0.493

High

917579

RDR1
Protein RDR1

1

0

High-throughput

0.493

High

381179

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381574

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

515285

RL35A
Large ribosomal subunit protein uL29A

1

1

Small-scale

0.479

High

632706

DBP4
ATP-dependent RNA helicase HCA4

1

4

High-throughput

0.479

High

689082

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

754307

DCA13
Protein SOF1

1

1

High-throughput

0.479

High

807109

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

823007

ATAD2
ATPase histone chaperone YTA7

1

2

High-throughput

0.479

High

864477

MTR4
ATP-dependent RNA helicase DOB1

1

1

Small-scale

0.479

High

879826

RL37A
Large ribosomal subunit protein eL37A

1

1

Small-scale

0.479

High

885026

RL4B
Large ribosomal subunit protein uL4B

1

2

Small-scale

0.479

High

902689

RL37B
Large ribosomal subunit protein eL37B

1

1

Small-scale

0.479

High

917539

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.479

High

917543

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

917544

H3
Histone H3

1

1

High-throughput

0.479

High

917554

RRB1
Ribosome assembly protein RRB1

1

1

High-throughput

0.479

High

917559

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

917565

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

917571

NOP12
Nucleolar protein 12

1

1

High-throughput

0.479

High

917578

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.479

High

917587

NOP58
Nucleolar protein 58

1

1

High-throughput

0.479

High

149865

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

382233

H4
Histone H4

1

0

High-throughput

0.458

High

410239

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

419816

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

435236

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436066

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

442018

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

448987

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

512550

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513389

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.458

High

534285

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.458

High

584929

TRM1
tRNA

1

0

High-throughput

0.458

High

585316

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

603083

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

673576

NLE1
Ribosome assembly protein 4

1

0

Small-scale

0.458

High

674731

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

677488

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

689561

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

694597

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

707694

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709882

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

735074

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

782173

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

791076

NOP4
Nucleolar protein 4

1

0

High-throughput

0.458

High

794199

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.458

High

795828

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

798267

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

806632

RIX1
Pre-rRNA-processing protein RIX1

1

0

High-throughput

0.458

High

809373

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

815181

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

826036

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

826677

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

844541

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

852580

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

863930

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.458

High

864934

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

917537

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

917540

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

917550

ARX1
Probable metalloprotease ARX1

1

0

Small-scale

0.458

High

917551

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

917553

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

917556

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

917560

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

917574

SGO1
Shugoshin

1

0

High-throughput

0.458

High

917581

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

917589

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

545630

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742019

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

819313

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

513532

RL1A
Large ribosomal subunit protein uL1A

1

2

Small-scale

0.437

High

712621

RL8B
Large ribosomal subunit protein eL8B

1

2

High-throughput

0.437

High

747480

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

524616

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

871497

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.279

Low

917576

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.279

Low

383800

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

438460

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.249

Low

455165

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503146

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504319

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513119

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514737

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

680602

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

0

High-throughput

0.249

Low

753480

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

778438

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

795108

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

802281

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812497

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

835841

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

917545

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

917546

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

917549

LIP1
Ceramide synthase subunit LIP1

1

0

High-throughput

0.249

Low

917566

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

917577

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

917575

FOLE
Folylpolyglutamate synthase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025