HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1312
+	Dm
		950423 H4_DROME (1-103): 4.51e-48: 150: 99.03		RAD50_DROME (1-1303): 1.57e-72: 268: 26.79
+	Hs
		724750 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		917676 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		917268 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Hs
		725132 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH10_HUMAN (44-596): 1.31e-16: 88.3: 13.20
+	Hs
		728462 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH11_HUMAN (46-651): 5.68e-16: 86: 8.67
+	Hs
		528404 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH8_HUMAN (41-622): 1.09e-14: 81.7: 9.42
+	Hs
		502906 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH3_HUMAN (785-1231): 2.95e-12: 74: 11.60
+	Mm
		93549 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		DESP_MOUSE (190-1069): 1.15e-11: 72: 18.72
+	Hs
		551658 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71
+	Hs
		148635 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Sc
		356275 H4_YEAST (18-103): 6.13e-41: 132: 90.70		USO1_YEAST (167-740): 7.25e-13: 75.7: 13.67
+	Hs
		149202 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15