HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 446
+	Sc
		356494 H4_YEAST (18-103): 6.13e-41: 132: 90.70		HAT2_YEAST (36-443): 3.11e-72: 234: 19.95
+	Hs
		903099 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		WDR5_HUMAN (248-445): 8.04e-48: 168: 21.72
+	Hs
		917881 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TBL1R_HUMAN (94-292): 5.97e-27: 115: 14.08
+	Sc
		356423 H4_YEAST (18-103): 6.13e-41: 132: 90.70		TAF5_YEAST (250-445): 1.54e-31: 129: 16.75
+	Dm
		950385 H4_DROME (1-103): 4.51e-48: 150: 99.03		CAF1_DROME (62-247): 5.03e-21: 96.6: 10.71
+	Hs
		917344 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		RBBP7_HUMAN (66-247): 3.57e-20: 94.3: 10.42
+	Hs
		917169 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71
+	Hs
		917320 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF5_HUMAN (297-445): 3.11e-19: 92.4: 11.44
+	Sp
		292788 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		HAT2_SCHPO (60-246): 5.25e-22: 99.7: 11.17
+	Zm
		74522 B4FD59_MAIZE (1-103): 3.47e-48: 150: 98.06		Q8W514_MAIZE (307-445): 4.82e-13: 72.7: 16.22
+	Sc
		356212 H4_YEAST (18-103): 6.13e-41: 132: 90.70		MSI1_YEAST (263-434): 2.3e-13: 73.6: 26.29