HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12590135
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1011
+	Hs
		880666 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		918151 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		140249 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		HDAC1_MOUSE (623-1009): 3.42e-140: 430: 23.49
+	Hs
		917226 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Dm
		950398 H4_DROME (1-103): 4.51e-48: 150: 99.03		HDAC1_DROME (625-1009): 4.99e-138: 426: 23.35
+	Hs
		177252 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC3_HUMAN (631-1007): 9.3e-131: 404: 22.34
+	Hs
		917682 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Sc
		356643 H4_YEAST (18-103): 6.13e-41: 132: 90.70		HDA1_YEAST (623-1008): 4.76e-134: 422: 34.64
+	Mm
		918237 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		HDAC2_MOUSE (622-1009): 1.69e-129: 402: 22.67
+	Sc
		356336 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RPD3_YEAST (619-1006): 1.04e-132: 409: 22.67
+	Hs
		918077 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC6_HUMAN (564-1009): 2e-107: 363: 30.95
+	Hs
		917872 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		HDAC8_HUMAN (623-962): 6.45e-24: 107: 28.45