HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	34079125, 33961781, 37071682
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 709
+	Hs
		420830 H2B1J_HUMAN (1-126): 6.62e-54: 166: 98.41		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996694 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996812 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996768 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		996816 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Ce
		136643 H2B1_CAEEL (6-126): 8.13e-50: 156: 79.34		SSP1B_CAEEL (1-695): 0: 648: 36.25
+	Ce
		136714 H2B4_CAEEL (22-126): 1.88e-48: 153: 87.62		SSP1B_CAEEL (1-695): 0: 648: 36.25
+	Hs
		1087421 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		918706 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		707756 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		241615 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		CIC_HUMAN (424-708): 7.87e-39: 157: 16.49
+	Hs
		1282968 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		297497 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		TOX4_HUMAN (484-678): 7.24e-32: 133: 23.86
+	Hs
		643302 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		643380 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449786 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		643248 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		567668 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52
+	Sc
		355755 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		NHP6A_YEAST (530-619): 6.02e-28: 109: 35.56
+	Hs
		175767 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		HMGB3_HUMAN (551-696): 3.34e-11: 65.2: 22.58