HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1128
+	Hs
		1043720 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		985569 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		Q05BL1_HUMAN (90-1128): 2.47e-152: 484: 99.90
+	Hs
		1274409 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38
+	Hs
		1087364 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		918638 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		707725 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		276167 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		PSD10_HUMAN (988-1128): 3e-43: 159: 16.77
+	Hs
		862088 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		DAPK1_HUMAN (791-1011): 1.31e-20: 100: 13.12
+	Hs
		1087341 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		918611 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1274461 H2B1H_HUMAN (1-126): 5.49e-54: 166: 99.21		DAPLE_HUMAN (33-349): 6.45e-16: 85.6: 16.36
+	Hs
		241653 H2B1K_HUMAN (1-126): 1.3e-53: 166: 99.21		DAPLE_HUMAN (33-349): 6.45e-16: 85.6: 16.36
+	Hs
		1231227 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1282945 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		918533 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		707690 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45