HitPredict

Interactor 1: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33961781, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 456
+	Hs
		1087495 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		707797 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1231264 H2B3B_HUMAN (1-126): 8.29e-52: 161: 95.24		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1282984 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1129867 H2B2F_HUMAN (1-126): 2.21e-54: 168: 98.41		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		1087493 H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		918777 H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		707796 H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		886220 H2B1D_HUMAN (1-126): 3.24e-53: 164: 99.21		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Dm
		355271 H2B_DROME (36-126): 9.18e-47: 148: 94.51		RUVB1_DROME (1-455): 0: 660: 79.56
+	Hs
		1282982 H2B1A_HUMAN (1-126): 3.14e-46: 147: 84.25		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Sc
		355997 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		RUVB1_YEAST (1-455): 0: 652: 67.39
+	Sc
		355620 H2B1_YEAST (3-125): 1.92e-36: 122: 71.55		RUVB1_YEAST (1-455): 0: 652: 67.39
+	Sc
		356054 H2B2_YEAST (3-125): 5.51e-37: 124: 71.55		RUVB2_YEAST (5-455): 0: 627: 41.72
+	Sc
		355704 H2B1_YEAST (3-125): 1.92e-36: 122: 71.55		RUVB2_YEAST (5-455): 0: 627: 41.72