HitPredict

Interactor 1: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0010008 - endosome membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 727
+	Hs
		893872 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		894409 RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08		CDC42_HUMAN (12-218): 7.09e-92: 286: 36.67
+	Hs
		564470 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RHOQ_HUMAN (10-225): 1.24e-84: 267: 36.53
+	Hs
		214190 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		SPOP_HUMAN (305-670): 2.13e-72: 241: 13.30
+	Hs
		545307 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RAC2_HUMAN (12-219): 9.54e-73: 236: 36.97
+	Hs
		892305 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RAC3_HUMAN (12-208): 3.69e-72: 234: 39.50
+	Hs
		918847 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		918849 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RHOG_HUMAN (12-218): 6.57e-71: 231: 36.19
+	Hs
		900355 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29
+	Hs
		913992 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RB11A_HUMAN (5-252): 2.31e-70: 230: 16.34
+	Hs
		918846 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RAB1A_HUMAN (1-236): 1.37e-70: 230: 16.87
+	Hs
		918916 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RAB2B_HUMAN (11-255): 1.87e-70: 230: 16.53
+	Hs
		918879 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RB11B_HUMAN (5-252): 6.51e-70: 229: 15.54
+	Hs
		918944 RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00		RAB1B_HUMAN (1-240): 2.33e-69: 227: 18.93
+	Mm
		919000 RAB1A_MOUSE (1-205): 4.45e-92: 269: 100.00		RAB1B_MOUSE (1-240): 3.46e-69: 227: 18.52
+	Zm
		73944 B4FAE1_MAIZE (4-204): 3.9e-87: 257: 78.71		B4FAE1_MAIZE (8-248): 1.8e-71: 233: 15.98
+	Hs
		925600 RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08		RAC1_HUMAN (12-220): 1.16e-71: 233: 35.38
+	Hs
		1273009 RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00		RAB1B_HUMAN (1-240): 2.33e-69: 227: 18.93
+	Hs
		900882 RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08		RHOA_HUMAN (16-216): 1.94e-70: 230: 35.29