HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	14690596
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 551
+	Hs
		849310 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		895779 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		851805 UB2E1_HUMAN (4-146): 8.81e-73: 217: 65.73		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		981791 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		587507 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587492 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51