Protein: FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1 (EC 2.7.11.1)

Gene: FRK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 114
UniProt ID: Q03002

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

393216

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.698

High

694167

CDC15
Cell division control protein 15

1

19

High-throughput

0.647

High

744013

RAD23
UV excision repair protein RAD23

1

8

High-throughput

0.647

High

757722

EDE1
EH domain-containing and endocytosis protein 1

1

10

High-throughput

0.647

High

763235

PP2C1
Protein phosphatase 2C homolog 1

1

20

High-throughput

0.647

High

800625

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

17

High-throughput

0.647

High

865958

DPH4
Diphthamide biosynthesis protein 4

1

9

High-throughput

0.647

High

925343

CRZ1
Transcriptional regulator CRZ1

1

4

High-throughput

0.647

High

1040416

TDA1
Serine/threonine-protein kinase TDA1

1

19

High-throughput

0.647

High

1040436

ARP8
Actin-like protein ARP8

1

20

High-throughput

0.647

High

1040428

NOP12
Nucleolar protein 12

1

16

High-throughput

0.618

High

925007

APJ1
J domain-containing protein APJ1

1

10

High-throughput

0.618

High

808776

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

0

High-throughput

0.614

High

548721

RNA1
Ran GTPase-activating protein 1

1

8

High-throughput

0.579

High

763107

RRP1
Ribosomal RNA-processing protein 1

2

2

High-throughput

0.565

High

637270

PWP1
Periodic tryptophan protein 1

1

12

High-throughput

0.536

High

793518

MAK5
ATP-dependent RNA helicase MAK5

1

17

High-throughput

0.536

High

808956

LCF3
Long-chain-fatty-acid--CoA ligase 3

1

3

High-throughput

0.536

High

1040439

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.536

High

1038815

LGE1
Transcriptional regulatory protein LGE1

2

1

High-throughput

0.521

High

817346

TPA1
Prolyl 3,4-dihydroxylase TPA1

1

0

High-throughput

0.513

High

455587

SYSC
Serine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

514954

YA11A
Transposon Ty1-A Gag polyprotein

1

1

High-throughput

0.501

High

518376

IF4A
ATP-dependent RNA helicase eIF4A

1

16

High-throughput

0.501

High

582252

AMPD
AMP deaminase

1

2

High-throughput

0.501

High

617866

DDR48
Stress protein DDR48

1

1

High-throughput

0.501

High

670327

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.501

High

692524

GYS2
Glycogen [starch] synthase isoform 2

1

1

High-throughput

0.501

High

701603

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

6

High-throughput

0.501

High

740311

PAH1
Phosphatidic acid phosphohydrolase 1

1

1

High-throughput

0.501

High

742930

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.501

High

744917

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

3

High-throughput

0.501

High

746662

DRS1
ATP-dependent RNA helicase DRS1

1

16

High-throughput

0.501

High

751274

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

4

High-throughput

0.501

High

763289

SGS1
ATP-dependent helicase SGS1

1

14

High-throughput

0.501

High

849579

COS4
Protein COS4

1

1

High-throughput

0.501

High

858121

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.501

High

1040423

ANT1
Peroxisomal adenine nucleotide transporter 1

1

16

High-throughput

0.501

High

1040437

YN11A
Transposon Ty1-NL1 Gag polyprotein

1

1

High-throughput

0.501

High

487965

TRNL
tRNA ligase

1

0

High-throughput

0.493

High

866158

YJ94
Uncharacterized membrane protein YJR124C

1

0

High-throughput

0.493

High

670201

MRM1
rRNA methyltransferase 1, mitochondrial

1

2

High-throughput

0.489

High

780702

RRP14
Ribosomal RNA-processing protein 14

1

1

High-throughput

0.489

High

782425

RPF2
Ribosome biogenesis protein RPF2

1

2

High-throughput

0.489

High

803920

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.489

High

816172

DPO5
rDNA transcriptional regulator POL5

1

2

High-throughput

0.489

High

825766

MAM33
Mitochondrial acidic protein MAM33

1

3

High-throughput

0.489

High

827588

RLP7
Ribosome biogenesis protein RLP7

1

5

High-throughput

0.489

High

918966

PESC
Pescadillo homolog

1

1

High-throughput

0.489

High

1040422

ERB1
Ribosome biogenesis protein ERB1

1

10

High-throughput

0.489

High

1040432

MAK21
Ribosome biogenesis protein MAK21

1

3

High-throughput

0.489

High

453988

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.480

High

763542

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.480

High

782270

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.480

High

803328

YAP3
AP-1-like transcription factor YAP3

1

0

High-throughput

0.480

High

849838

BUD27
Bud site selection protein 27

1

0

High-throughput

0.480

High

849925

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

866018

ADK
Adenosine kinase

1

0

High-throughput

0.480

High

866304

YJ9S
Uncharacterized protein YJR154W

1

0

High-throughput

0.480

High

918241

YG1B
Uncharacterized protein YGR017W

1

0

High-throughput

0.480

High

1040418

GIR2
Protein GIR2

1

0

High-throughput

0.480

High

1040427

HBT1
Protein HBT1

1

0

High-throughput

0.480

High

1040429

AB140
tRNA(Thr)

1

0

High-throughput

0.480

High

1040431

PLP2
Phosducin-like protein 2

1

0

High-throughput

0.480

High

1040435

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.480

High

709945

BMH1
Protein BMH1

1

20

High-throughput

0.479

High

760333

BMH2
Protein BMH2

1

20

High-throughput

0.479

High

1025015

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.479

High

1040426

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

735438

TREA
Cytosolic neutral trehalase

1

0

High-throughput

0.458

High

478424

EI2BG
Translation initiation factor eIF2B subunit gamma

1

1

High-throughput

0.457

High

600709

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.457

High

609238

CLC1
Clathrin light chain

1

4

High-throughput

0.457

High

610189

PDI
Protein disulfide-isomerase

1

4

High-throughput

0.457

High

619172

IF5A2
Eukaryotic translation initiation factor 5A-2

1

1

High-throughput

0.457

High

677833

YCZ0
Uncharacterized protein YCR100C

1

1

High-throughput

0.457

High

739739

SPT16
FACT complex subunit SPT16

1

3

High-throughput

0.457

High

751159

SFC1
Succinate/fumarate mitochondrial transporter

1

15

High-throughput

0.457

High

797161

AIM3
Altered inheritance of mitochondria protein 3

1

10

High-throughput

0.457

High

801704

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

4

High-throughput

0.457

High

917993

MST27
Multicopy suppressor of SEC21 protein 27

1

1

High-throughput

0.457

High

919710

REXO1
RNA exonuclease 1

1

1

High-throughput

0.457

High

923925

VPS75
Vacuolar protein sorting-associated protein 75

1

1

High-throughput

0.457

High

924688

ESBP6
Uncharacterized transporter ESBP6

1

3

High-throughput

0.457

High

1040415

NHP10
Non-histone protein 10

1

8

High-throughput

0.457

High

1040417

YMD7
Uncharacterized protein YML037C

1

1

High-throughput

0.457

High

1040424

BFR2
Protein BFR2

1

1

High-throughput

0.457

High

1040425

BRE1
E3 ubiquitin-protein ligase BRE1

1

20

High-throughput

0.457

High

524937

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

546015

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.445

High

804401

SSZ1
Ribosome-associated complex subunit SSZ1

1

14

High-throughput

0.445

High

824527

6P21
6-phosphofructo-2-kinase 1

1

4

High-throughput

0.445

High

795174

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

826777

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

1040420

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

1040421

PDS5
Sister chromatid cohesion protein PDS5

1

2

High-throughput

0.437

High

635409

SAG1
Alpha-agglutinin

1

0

High-throughput

0.269

Low

357781

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.261

Low

454662

RAD2
DNA repair protein RAD2

1

0

High-throughput

0.261

Low

645085

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.261

Low

736713

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.261

Low

779835

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

1

0

High-throughput

0.261

Low

780381

ELF1
Transcription elongation factor 1

1

0

High-throughput

0.261

Low

796294

YBQ3
Uncharacterized protein YBR053C

1

0

High-throughput

0.261

Low

800268

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.261

Low

823211

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.261

Low

866268

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.261

Low

866272

YJ9J
Uncharacterized protein YJR142W

1

0

High-throughput

0.261

Low

917764

GUP1
Membrane-bound O-acyltransferase GUP1

1

0

High-throughput

0.261

Low

1040419

YM30
Uncharacterized membrane protein YMR155W

1

0

High-throughput

0.261

Low

1040430

YIG1
Protein YIG1

1

0

High-throughput

0.261

Low

1040433

TM115
Transmembrane protein 115 homolog

1

0

High-throughput

0.261

Low

1040434

ATP14
ATP synthase subunit H, mitochondrial

1

0

High-throughput

0.261

Low

1040438

GDIR
Rho GDP-dissociation inhibitor

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025