HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: PELI1 (Q96FA3)
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1)
Gene: PELI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19264966
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0061630 - ubiquitin protein ligase activity GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 418
+	Hs
		849407 UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		895877 UB2D3_HUMAN (1-147): 1.54e-81: 238: 97.28		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		896518 UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		896491 UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22		PELI3_HUMAN (3-418): 0: 696: 66.67