HitPredict

Interactor 1: RS30 (P62861)
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (FAU ubiquitin like and ribosomal protein S30 fusion) [Cleaved into: Ubiquitin-like protein FUBI; Small ribosomal subunit protein eS30 (40S ribosomal protein S30)]
Gene: FAU

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 947
+	Hs
		681774 RL40_HUMAN (1-96): 4.39e-41: 134: 29.59		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Hs
		681773 RS27A_HUMAN (1-75): 3.06e-32: 112: 35.07		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Hs
		474936 UBB_HUMAN (1-74): 2.51e-28: 105: 35.53		AKT2_HUMAN (286-701): 1.96e-133: 411: 20.32
+	Hs
		474935 UBB_HUMAN (1-74): 2.51e-28: 105: 35.53		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Hs
		475012 UBB_HUMAN (1-74): 2.51e-28: 105: 35.53		STK4_HUMAN (405-650): 2.6e-99: 321: 30.80
+	Hs
		924440 RL40_HUMAN (1-96): 4.39e-41: 134: 29.59		M3K2_HUMAN (386-626): 1.28e-24: 112: 33.60
+	Hs
		924395 RL40_HUMAN (1-96): 4.39e-41: 134: 29.59		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		924221 RS27A_HUMAN (1-75): 3.06e-32: 112: 35.07		M3K2_HUMAN (386-626): 1.28e-24: 112: 33.60
+	Hs
		924126 RS27A_HUMAN (1-75): 3.06e-32: 112: 35.07		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		475017 UBB_HUMAN (1-74): 2.51e-28: 105: 35.53		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		475248 UBB_HUMAN (1-74): 2.51e-28: 105: 35.53		M3K2_HUMAN (386-626): 1.28e-24: 112: 33.60
+	Hs
		1306392 Q9UFQ0_HUMAN (1-74): 3.1e-28: 105: 35.53		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		475158 UBB_HUMAN (1-74): 2.51e-28: 105: 35.53		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14