HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32877691, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 412
+	Hs
		118719 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		1151058 Q6FHM2_HUMAN (1-340): 1e-105: 314: 90.29		FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43
+	Hs
		1334923 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43
+	Hs
		154682 GNB5_HUMAN (129-340): 1.35e-45: 161: 21.46		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		921535 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		684815 Q6FHM2_HUMAN (1-340): 1e-105: 314: 90.29		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		684612 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		920946 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		SPAG1_HUMAN (225-336): 6.7e-16: 82.1: 20.54
+	Hs
		1123958 Q59G26_HUMAN (5-298): 3.7e-62: 202: 16.89		FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43
+	Hs
		118777 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		684951 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		118764 POC1B_HUMAN (1-85): 1.01e-16: 82.7: 16.47		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		154657 GNB5_HUMAN (129-340): 1.35e-45: 161: 21.46		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		972550 POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Sc
		549699 PRP4_YEAST (53-212): 5.13e-14: 74.3: 26.22		STI1_YEAST (221-371): 6.12e-25: 108: 19.21
+	Hs
		196960 PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00