Protein: HAT1
Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1)

Gene: HAT1
Organism: Homo sapiens
Interactions: 171
UniProt ID: O14929

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0004402 - histone acetyltransferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158770

H31
Histone H3.1

14

8

Small-scale

0.759

High

158797

RBBP7
Histone-binding protein RBBP7

9

5

Small-scale

0.753

High

158767

H4
Histone H4

7

5

Small-scale

0.752

High

158776

RBBP4
Histone-binding protein RBBP4

4

5

High-throughput

0.705

High

158871

ASF1A
Histone chaperone ASF1A

4

2

High-throughput

0.704

High

158861

ASF1B
Histone chaperone ASF1B

4

2

Small-scale

0.699

High

158834

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

4

0

Small-scale

0.653

High

158774

REL
Proto-oncogene c-Rel

3

0

High-throughput

0.646

High

158772

H33
Histone H3.3

3

8

Small-scale

0.640

High

158761

MEOX2
Homeobox protein MOX-2

2

1

High-throughput

0.633

High

158793

EZH2
Histone-lysine N-methyltransferase EZH2

2

1

Small-scale

0.624

High

158799

H31T
Histone H3.1t

2

8

Small-scale

0.602

High

158756

NASP
Nuclear autoantigenic sperm protein

2

0

High-throughput

0.602

High

158841

Z512B
Zinc finger protein 512B

2

0

High-throughput

0.585

High

158777

EP300
Histone acetyltransferase p300

2

1

High-throughput

0.584

High

158795

SNPC1
snRNA-activating protein complex subunit 1

2

0

High-throughput

0.580

High

158828

ZSCA4
Zinc finger and SCAN domain-containing protein 4

2

0

High-throughput

0.580

High

158844

TRIB3
Tribbles homolog 3

2

0

High-throughput

0.580

High

158855

STEEP
STING ER exit protein

2

0

High-throughput

0.580

High

158709

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

158736

ITF2
Transcription factor 4

1

0

High-throughput

0.549

High

158788

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

0

High-throughput

0.549

High

158754

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

0

High-throughput

0.547

High

158832

RSAD2
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2

1

0

Small-scale

0.537

High

156984

AIM2
Interferon-inducible protein AIM2

1

2

High-throughput

0.536

High

158723

SEMG1
Semenogelin-1

1

1

High-throughput

0.536

High

158726

KLK3
Prostate-specific antigen

1

1

High-throughput

0.536

High

158738

H2AX
Histone H2AX

1

2

Small-scale

0.536

High

158773

SEMG2
Semenogelin-2

1

1

High-throughput

0.536

High

158798

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.536

High

158752

5HT2B
5-hydroxytryptamine receptor 2B

1

0

High-throughput

0.518

High

158811

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

158719

CYTA
Cystatin-A

1

0

High-throughput

0.513

High

158727

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.513

High

158735

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

158741

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.513

High

158787

CUL3
Cullin-3

1

0

High-throughput

0.513

High

158823

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

158835

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

158866

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

158743

1433T
14-3-3 protein theta

1

2

High-throughput

0.501

High

158800

H2A2C
Histone H2A type 2-C

1

2

Small-scale

0.501

High

158784

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.493

High

158837

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.493

High

62810

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

1

High-throughput

0.489

High

158762

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

158766

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

Small-scale

0.480

High

158710

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

158714

MTA2
Metastasis-associated protein MTA2

1

2

High-throughput

0.479

High

158718

MBD3
Methyl-CpG-binding domain protein 3

1

1

High-throughput

0.479

High

158729

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

158737

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

158740

MCM3
DNA replication licensing factor MCM3

1

1

High-throughput

0.479

High

158745

SMCA1
Probable global transcription activator SNF2L1

1

2

High-throughput

0.479

High

158753

ATRX
Transcriptional regulator ATRX

1

3

High-throughput

0.479

High

158757

CENPA
Histone H3-like centromeric protein A

1

8

High-throughput

0.479

High

158768

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.479

High

158771

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

158778

BPTF
Nucleosome-remodeling factor subunit BPTF

1

4

High-throughput

0.479

High

158779

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.479

High

158781

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

158783

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

158785

MTA1
Metastasis-associated protein MTA1

1

2

High-throughput

0.479

High

158789

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

158791

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

2

High-throughput

0.479

High

158792

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

4

High-throughput

0.479

High

158803

ARI4B
AT-rich interactive domain-containing protein 4B

1

1

High-throughput

0.479

High

158804

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

1

High-throughput

0.479

High

158812

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

158817

UBN2
Ubinuclein-2

1

1

High-throughput

0.479

High

158821

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.479

High

158830

IPO4
Importin-4

1

1

Small-scale

0.479

High

158833

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.479

High

158847

MTA3
Metastasis-associated protein MTA3

1

2

High-throughput

0.479

High

158857

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

1

High-throughput

0.479

High

158859

UBN1
Ubinuclein-1

1

1

High-throughput

0.479

High

158860

HELLS
Lymphoid-specific helicase

1

3

Small-scale

0.479

High

158864

MBD2
Methyl-CpG-binding domain protein 2

1

1

High-throughput

0.479

High

158869

XPO7
Exportin-7

1

1

High-throughput

0.479

High

146771

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

158707

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

158708

PHF1
PHD finger protein 1

1

0

High-throughput

0.458

High

158711

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

158712

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.458

High

158713

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

158720

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

158721

ESR1
Estrogen receptor

1

0

High-throughput

0.458

High

158724

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

158730

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

158731

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

158732

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

158733

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

158739

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.458

High

158742

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.458

High

158744

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

158746

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

158747

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

158748

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

158750

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

158751

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

158755

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

158760

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

158763

HMGA2
High mobility group protein HMGI-C

1

0

Small-scale

0.458

High

158764

HIRA
Protein HIRA

1

0

High-throughput

0.458

High

158775

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.458

High

158780

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

158782

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

158786

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

158790

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

158794

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

158802

CRY2
Cryptochrome-2

1

0

High-throughput

0.458

High

158807

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

158810

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

158818

ASXL2
Putative Polycomb group protein ASXL2

1

0

High-throughput

0.458

High

158819

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

158820

TLK2
Serine/threonine-protein kinase tousled-like 2

1

0

High-throughput

0.458

High

158824

CDAN1
Codanin-1

1

0

High-throughput

0.458

High

158825

BAP18
Chromatin complexes subunit BAP18

1

0

High-throughput

0.458

High

158826

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

Small-scale

0.458

High

158831

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

158836

IRF7
Interferon regulatory factor 7

1

0

Small-scale

0.458

High

158839

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

158843

PWP2A
PWWP domain-containing protein 2A

1

0

High-throughput

0.458

High

158845

SIN3A
Paired amphipathic helix protein Sin3a

1

0

High-throughput

0.458

High

158848

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

158850

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

158851

SP130
Histone deacetylase complex subunit SAP130

1

0

High-throughput

0.458

High

158853

BC11A
B-cell lymphoma/leukemia 11A

1

0

High-throughput

0.458

High

158856

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

158862

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

158863

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

158865

KS6B2
Ribosomal protein S6 kinase beta-2

1

0

High-throughput

0.458

High

158867

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

158870

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

158872

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.458

High

158873

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

Small-scale

0.458

High

158874

CABIN
Calcineurin-binding protein cabin-1

1

0

High-throughput

0.458

High

158758

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.438

High

158816

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

158725

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

158805

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

158822

LACC1
Purine nucleoside phosphorylase LACC1

1

0

Small-scale

0.426

High

158849

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

158759

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

158722

VTNC
Vitronectin

2

0

High-throughput

0.328

High

158806

KANK4
KN motif and ankyrin repeat domain-containing protein 4

2

0

High-throughput

0.316

High

158808

MORN5
MORN repeat-containing protein 5

2

0

High-throughput

0.316

High

158842

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

158734

NCF1
Neutrophil cytosol factor 1

1

0

High-throughput

0.279

Low

158769

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.279

Low

158813

AAGAB
Alpha- and gamma-adaptin-binding protein p34

1

0

High-throughput

0.279

Low

158838

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.279

Low

158852

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

0

High-throughput

0.279

Low

158728

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

0

Small-scale

0.261

Low

158715

RHBT1
Rho-related BTB domain-containing protein 1

1

0

High-throughput

0.249

Low

158717

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

158749

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.249

Low

158765

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.249

Low

158801

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

158809

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.249

Low

158814

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

158815

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

158840

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

158846

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.249

Low

158854

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

158858

F204A
Protein FAM204A

1

0

High-throughput

0.249

Low

158868

HMGX4
HMG domain-containing protein 4

1

0

High-throughput

0.249

Low

158716

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.232

Low

158796

B2LA1
Bcl-2-related protein A1

1

0

Small-scale

0.232

Low

158827

S15A4
Solute carrier family 15 member 4

1

0

Small-scale

0.232

Low

158829

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024