HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: HDAC5 (Q9UQL6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)
Gene: HDAC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16221676
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 1122
+	Hs
		921778 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		880669 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		903610 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		921762 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97
+	Hs
		1334921 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97
+	Hs
		921074 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97
+	Hs
		1270370 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		903202 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		903404 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Hs
		177249 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57