Interactor 1: RBX1 (P62877)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)]
Gene: RBX1

Interactor 2: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 31253590, 12048197, 33504946, 35551201, 12149480
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ubiquitin~zf-rbx1
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0031462 - Cul2-RING ubiquitin ligase complex
GO:0031466 - Cul5-RING ubiquitin ligase complex
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 108
Hs

1 118
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024