HitPredict

Interactor 1: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Interactor 2: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28225217, 21145461
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 913
+	Hs
		923676 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		203519 PPIH_HUMAN (2-164): 1.38e-84: 247: 53.85		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		834741 RBP2_HUMAN (3-164): 1.87e-73: 240: 66.67		CUL3_HUMAN (186-913): 0: 853: 37.19
+	Hs
		923674 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		834739 RBP2_HUMAN (3-164): 1.87e-73: 240: 66.67		CUL1_HUMAN (213-913): 0: 778: 30.16
+	Hs
		923675 PPIA_HUMAN (1-165): 2.77e-91: 264: 100.00		CUL2_HUMAN (205-913): 0: 746: 27.53
+	Hs
		834740 RBP2_HUMAN (3-164): 1.87e-73: 240: 66.67		CUL2_HUMAN (205-913): 0: 746: 27.53