Protein: RCAN1
Calcipressin-1 (Adapt78) (Down syndrome critical region protein 1) (Myocyte-enriched calcineurin-interacting protein 1) (MCIP1) (Regulator of calcineurin 1)

Gene: RCAN1
Organism: Homo sapiens
Interactions: 56
UniProt ID: P53805

Gene Ontology (top 5):
GO:0002931 - response to ischemia
GO:0003676 - nucleic acid binding
GO:0004864 - protein phosphatase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

923657

PP2BA
Protein phosphatase 3 catalytic subunit alpha

7

11

Small-scale

0.749

High

593824

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

5

11

High-throughput

0.722

High

873451

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

5

11

High-throughput

0.716

High

923656

CANB1
Calcineurin subunit B type 1

4

7

High-throughput

0.700

High

891081

GSK3A
Glycogen synthase kinase-3 alpha

3

3

High-throughput

0.662

High

923667

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

3

0

High-throughput

0.638

High

479917

CYTT
Cystatin-SA

2

5

High-throughput

0.628

High

891393

GSK3B
Glycogen synthase kinase-3 beta

2

3

High-throughput

0.628

High

923665

PAUF
Pancreatic adenocarcinoma up-regulated factor

2

1

High-throughput

0.628

High

923673

ARMT1
Damage-control phosphatase ARMT1

3

2

High-throughput

0.604

High

923680

FBW1A
F-box/WD repeat-containing protein 1A

1

1

Small-scale

0.561

High

923653

RCAN1
Calcipressin-1

1

0

Small-scale

0.554

High

873068

SOX9
Transcription factor SOX-9

1

1

High-throughput

0.541

High

923654

SOX10
Transcription factor SOX-10

1

1

High-throughput

0.541

High

370061

CYTS
Cystatin-S

1

5

High-throughput

0.536

High

702392

CYTD
Cystatin-D

1

5

High-throughput

0.536

High

923668

CANB2
Calcineurin subunit B type 2

1

7

High-throughput

0.536

High

923679

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

Small-scale

0.529

High

143417

E2F3
Transcription factor E2F3

1

0

High-throughput

0.518

High

244077

ZN292
Zinc finger protein 292

1

0

High-throughput

0.518

High

923660

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.518

High

923661

NDF2
Neurogenic differentiation factor 2

1

0

High-throughput

0.518

High

923663

CXXC5
CXXC-type zinc finger protein 5

1

0

High-throughput

0.518

High

923670

ZN350
Zinc finger protein 350

1

0

High-throughput

0.518

High

923674

PICK1
PRKCA-binding protein

1

0

High-throughput

0.518

High

923678

PRDM4
PR domain zinc finger protein 4

1

0

High-throughput

0.518

High

923662

HIKES
Protein Hikeshi

1

0

High-throughput

0.513

High

517213

AMY1B
Alpha-amylase 1B

2

1

High-throughput

0.504

High

905530

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

Small-scale

0.493

High

923671

TOLIP
Toll-interacting protein

1

0

Small-scale

0.493

High

923681

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.493

High

421778

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

923677

FBW1B
F-box/WD repeat-containing protein 11

1

1

Small-scale

0.479

High

923669

CTSR2
Cation channel sperm-associated protein 2

1

1

High-throughput

0.470

High

400532

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

Small-scale

0.458

High

461304

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

913122

STAT2
Signal transducer and activator of transcription 2

1

0

Small-scale

0.458

High

923672

TAOK3
Serine/threonine-protein kinase TAO3

1

0

High-throughput

0.458

High

457067

CAN1
Calpain-1 catalytic subunit

1

2

Small-scale

0.445

High

516396

CALM2
Calmodulin-2

1

2

High-throughput

0.445

High

516486

CALM3
Calmodulin-3

1

2

High-throughput

0.445

High

923655

FBXW4
F-box/WD repeat-containing protein 4

1

2

Small-scale

0.437

High

563469

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

651633

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

Small-scale

0.426

High

923658

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

379629

IGHA1
Immunoglobulin heavy constant alpha 1

1

1

High-throughput

0.407

High

288166

CLC3A
C-type lectin domain family 3 member A

2

0

High-throughput

0.328

High

923664

SRBD1
S1 RNA-binding domain-containing protein 1

2

0

High-throughput

0.328

High

155927

SOCS3
Suppressor of cytokine signaling 3

1

0

Small-scale

0.292

High

658875

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

0

High-throughput

0.282

High

923659

SPRL1
SPARC-like protein 1

1

0

High-throughput

0.282

High

923676

RM15
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

605131

KCRS
Creatine kinase S-type, mitochondrial

1

0

High-throughput

0.232

Low

923666

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.232

Low

923675

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025