Interactor 1: HCH1 (P53834)
Hsp90 co-chaperone HCH1 (High-copy Hsp90 suppressor protein 1)
Gene: HCH1
Interactor 2: AHA1 (Q12449)
Hsp90 co-chaperone AHA1 (Activator of Hsp90 ATPase protein 1)
Gene: AHA1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.66 | 1.00 | 0.814 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 14739935, 12604615, unassigned1933 |
| Identification Methods | x-ray crystallography, two hybrid, dihydrofolate reductase reconstruction |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aha1_N~Aha1_N |
| Common GO terms | GO:0001671 - ATPase activator activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding and 1 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
