HitPredict

Interactor 1: AP2B1 (P62944)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: EPN2 (Q9Z1Z3)
Epsin-2 (EPS-15-interacting protein 2)
Gene: EPN2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16903783
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030276 - clathrin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 937 Rn			1 583
+	Hs
		307524 AP2B1_HUMAN (1-937): 0: 926: 100.00		EPN2_HUMAN (1-583): 6.5e-90: 292: 69.89
+	Hs
		925867 AP2B1_HUMAN (1-937): 0: 926: 100.00		EPN4_HUMAN (3-580): 1.03e-86: 283: 23.20
+	Hs
		1014011 AP1B1_HUMAN (1-937): 0: 888: 82.72		EPN4_HUMAN (3-580): 1.03e-86: 283: 23.20
+	Rn
		291389 AP2B1_RAT (1-937): 0: 926: 100.00		EPN1_RAT (1-563): 1.03e-67: 231: 41.35
+	Hs
		926065 AP2B1_HUMAN (1-937): 0: 926: 100.00		EPN1_HUMAN (1-563): 2.51e-65: 225: 41.28
+	Hs
		1014105 AP1B1_HUMAN (1-937): 0: 888: 82.72		EPN1_HUMAN (1-563): 2.51e-65: 225: 41.28
+	Dm
		1096902 Q24253_DROME (1-937): 0: 804: 71.75		Q8IN05_DROME (3-434): 3.52e-91: 308: 25.66
+	Hs
		253738 AP2B1_HUMAN (1-937): 0: 926: 100.00		AUXI_HUMAN (221-544): 1.75e-43: 168: 17.11
+	Dm
		1096905 Q24253_DROME (1-937): 0: 804: 71.75		Q9VD13_DROME (3-579): 2.86e-73: 248: 22.84
+	Hs
		203219 AP2B1_HUMAN (1-937): 0: 926: 100.00		SYNJ1_HUMAN (165-560): 2.85e-15: 81.6: 11.06
+	Hs
		926047 AP2B1_HUMAN (1-937): 0: 926: 100.00		MAGL2_HUMAN (286-575): 9.49e-09: 60.4: 15.59
+	Hs
		203223 AP1B1_HUMAN (1-937): 0: 888: 82.72		SYNJ1_HUMAN (165-560): 2.85e-15: 81.6: 11.06
+	Hs
		321545 AP2A1_HUMAN (11-932): 0: 634: 16.97		EPN4_HUMAN (3-580): 1.03e-86: 283: 23.20
+	Hs
		302148 AP2A2_HUMAN (11-933): 0: 600: 16.99		EPN4_HUMAN (3-580): 1.03e-86: 283: 23.20
+	Hs
		321680 AP2A1_HUMAN (11-932): 0: 634: 16.97		EPN1_HUMAN (1-563): 2.51e-65: 225: 41.28
+	Rn
		88757 D3ZUY8_RAT (11-932): 0: 625: 17.14		EPN1_RAT (1-563): 1.03e-67: 231: 41.35
+	Rn
		291387 AP2A2_RAT (11-932): 0: 595: 16.50		EPN1_RAT (1-563): 1.03e-67: 231: 41.35
+	Hs
		302230 AP2A2_HUMAN (11-933): 0: 600: 16.99		EPN1_HUMAN (1-563): 2.51e-65: 225: 41.28
+	Hs
		253720 AP2A1_HUMAN (11-932): 0: 634: 16.97		AUXI_HUMAN (221-544): 1.75e-43: 168: 17.11
+	Hs
		203194 AP2A1_HUMAN (11-932): 0: 634: 16.97		SYNJ1_HUMAN (165-560): 2.85e-15: 81.6: 11.06