HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Interactor 2: NLRP1 (Q9C000)
NACHT, LRR and PYD domains-containing protein 1 (EC 3.4.-.-) (EC 3.6.4.-) (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]
Gene: NLRP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CARD~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 1473
+	At
		1092049 UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59		FLS2_ARATH (579-1213): 2.09e-78: 285: 11.35
+	At
		1092449 UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59		BRL2_ARATH (846-1224): 7.86e-50: 196: 12.76
+	Hs
		527977 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		RINI_HUMAN (676-928): 1.87e-19: 95.2: 22.22
+	At
		1092125 UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59		BRL3_ARATH (1032-1272): 7.16e-10: 66: 10.54