Protein: SBDS
Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein)

Gene: SBDS
Organism: Homo sapiens
Interactions: 152
UniProt ID: Q9Y3A5

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0001833 - inner cell mass cell proliferation
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1275909

EFL1
Elongation factor-like GTPase 1

1

2

Small-scale

0.692

High

1404861

RING2
E3 ubiquitin-protein ligase RING2

2

1

Small-scale

0.644

High

709031

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

1358227

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.602

High

556889

MYH1
Myosin-1

2

5

High-throughput

0.584

High

563080

MYH8
Myosin-8

2

5

High-throughput

0.584

High

1461304

MYH13
Myosin-13

2

5

High-throughput

0.584

High

1227753

A16L1
Autophagy-related protein 16-1

2

1

High-throughput

0.571

High

1383385

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.549

High

985964

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.536

High

1121927

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

7

High-throughput

0.536

High

1247727

RSLBA
Ras-like protein family member 11A

1

1

High-throughput

0.536

High

1288827

KTN1
Kinectin

1

6

High-throughput

0.536

High

1434433

GSX1
GS homeobox 1

1

1

High-throughput

0.536

High

1491121

MTCL1
Microtubule cross-linking factor 1

1

7

High-throughput

0.536

High

928598

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.529

High

1450192

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.529

High

1452490

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.529

High

1361980

KLHL6
Kelch-like protein 6

1

0

High-throughput

0.518

High

1143316

PLEC
Plectin

1

1

High-throughput

0.515

High

1448197

SPTN5
Spectrin beta chain, non-erythrocytic 5

1

1

High-throughput

0.515

High

184047

CLIC2
Chloride intracellular channel protein 2

1

0

High-throughput

0.513

High

187217

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

603697

JUNB
Transcription factor JunB

1

0

High-throughput

0.513

High

612021

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

614756

ARY1
Arylamine N-acetyltransferase 1

1

0

High-throughput

0.513

High

651037

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.513

High

720899

KPYR
Pyruvate kinase PKLR

1

0

High-throughput

0.513

High

777335

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.513

High

854461

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

0

High-throughput

0.513

High

1025236

HXC5
Homeobox protein Hox-C5

1

0

High-throughput

0.513

High

1106760

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.513

High

1211658

FBP1L
Formin-binding protein 1-like

1

0

High-throughput

0.513

High

1271695

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.513

High

1277452

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.513

High

1329026

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.513

High

1335095

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

1339356

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.513

High

1371994

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

1387126

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.513

High

1416361

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.513

High

1417216

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

1429408

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.513

High

1432953

UN45A
Protein unc-45 homolog A

1

0

High-throughput

0.513

High

1433250

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

0

High-throughput

0.513

High

1435485

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1435982

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.513

High

1446640

SCRT2
Transcriptional repressor scratch 2

1

0

High-throughput

0.513

High

1450397

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.513

High

1450666

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.513

High

1453637

ZIM2
Zinc finger imprinted 2

1

0

High-throughput

0.513

High

1461530

INTU
Protein inturned

1

0

High-throughput

0.513

High

1461820

NP1L2
Nucleosome assembly protein 1-like 2

1

0

High-throughput

0.513

High

1491072

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.513

High

553445

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

1

High-throughput

0.489

High

939552

FCGRN
IgG receptor FcRn large subunit p51

1

1

High-throughput

0.489

High

1280236

MILR1
Allergin-1

1

1

High-throughput

0.489

High

1101203

CLN3
Battenin

1

1

Small-scale

0.481

High

522026

H14
Histone H1.4

1

1

Small-scale

0.479

High

556969

MYH7
Myosin-7

1

5

High-throughput

0.479

High

596437

H12
Histone H1.2

1

1

Small-scale

0.479

High

650500

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.479

High

810472

RL3
Large ribosomal subunit protein uL3

1

1

Small-scale

0.479

High

1039464

RL6
Large ribosomal subunit protein eL6

1

1

Small-scale

0.479

High

1062729

DHX9
ATP-dependent RNA helicase A

1

1

Small-scale

0.479

High

1137204

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.479

High

1421028

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1461299

MYH2
Myosin-2

1

5

High-throughput

0.479

High

1491122

MYH4
Myosin-4

1

5

High-throughput

0.479

High

386391

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

260640

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

289736

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

0

High-throughput

0.458

High

346539

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

373571

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

414896

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

429071

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

446482

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

447607

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

553298

KCRB
Creatine kinase B-type

1

0

High-throughput

0.458

High

559550

XRCC5
X-ray repair cross-complementing protein 5

1

0

Small-scale

0.458

High

612833

RL7
Large ribosomal subunit protein uL30

1

0

Small-scale

0.458

High

620670

NUCL
Nucleolin

1

0

Small-scale

0.458

High

658487

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

686538

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.458

High

696936

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

Small-scale

0.458

High

717005

RL12
Large ribosomal subunit protein uL11

1

0

Small-scale

0.458

High

785548

RL4
Large ribosomal subunit protein uL4

1

0

Small-scale

0.458

High

799602

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

848455

MAGA6
Melanoma-associated antigen 6

1

0

High-throughput

0.458

High

859514

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.458

High

898898

RL14
Large ribosomal subunit protein eL14

1

0

Small-scale

0.458

High

910744

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

Small-scale

0.458

High

976044

RL7A
Large ribosomal subunit protein eL8

1

0

Small-scale

0.458

High

986290

RL8
Large ribosomal subunit protein uL2

1

0

Small-scale

0.458

High

1008412

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

Small-scale

0.458

High

1027869

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

Small-scale

0.458

High

1057972

RL18
Large ribosomal subunit protein eL18

1

0

Small-scale

0.458

High

1060005

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

High-throughput

0.458

High

1122593

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1155934

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1256208

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1361945

TITIN
Titin

1

0

High-throughput

0.458

High

1370484

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1410785

MBB1A
Myb-binding protein 1A

1

0

Small-scale

0.458

High

1434298

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1447871

DDX21
Nucleolar RNA helicase 2

1

0

Small-scale

0.458

High

1453327

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

0

Small-scale

0.458

High

1459406

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1449676

RBM12
RNA-binding protein 12

1

2

High-throughput

0.445

High

711959

LTK
Leukocyte tyrosine kinase receptor

1

1

High-throughput

0.437

High

787105

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

1

High-throughput

0.437

High

1251985

LMTK1
Serine/threonine-protein kinase LMTK1

1

2

High-throughput

0.437

High

1400431

LMTK3
Serine/threonine-protein kinase LMTK3

1

3

High-throughput

0.437

High

125673

LEG9
Galectin-9

1

0

High-throughput

0.426

High

135739

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.426

High

354811

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

530637

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

598797

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

956554

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.426

High

959429

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.426

High

1010796

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.426

High

1131861

LBR
Delta(14)-sterol reductase LBR

1

0

High-throughput

0.426

High

1154307

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

0

High-throughput

0.426

High

1209820

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1446864

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

0

High-throughput

0.426

High

1447529

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.426

High

1462722

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

1491006

SGT1
Protein SGT1 homolog

1

0

High-throughput

0.426

High

1392423

SYMM
Methionine--tRNA ligase, mitochondrial

1

1

High-throughput

0.407

High

887367

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

416054

CP1A1
Cytochrome P450 1A1

3

0

High-throughput

0.347

High

387925

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.328

High

941380

CAV3
Caveolin-3

2

0

High-throughput

0.328

High

458026

TRY2
Trypsin-2

1

0

High-throughput

0.279

Low

534339

CD8B
T-cell surface glycoprotein CD8 beta chain

1

0

High-throughput

0.279

Low

651612

IBP4
Insulin-like growth factor-binding protein 4

1

0

High-throughput

0.279

Low

1331309

NIPA2
Magnesium transporter NIPA2

1

0

High-throughput

0.279

Low

1408257

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

1451130

TMM51
Transmembrane protein 51

1

0

High-throughput

0.279

Low

1458728

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.279

Low

1490764

NTNG1
Netrin-G1

1

0

High-throughput

0.279

Low

377794

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

380203

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

418532

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

720371

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.249

Low

1418542

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1435105

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low

224530

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.232

Low

261329

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

689874

CD27
CD27 antigen

1

0

High-throughput

0.232

Low

1104172

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1447619

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025