HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: DNJC4 (Q9NNZ3)
DnaJ homolog subfamily C member 4 (DnaJ-like protein HSPF2) (Multiple endocrine neoplasia type 1 candidate protein number 18)
Gene: DNAJC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 241
+	Hs
		924780 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJA3_HUMAN (3-191): 5.67e-43: 153: 21.69
+	Hs
		924923 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJB4_HUMAN (33-236): 2.36e-43: 151: 17.83
+	Hs
		924921 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DJB11_HUMAN (33-134): 3.08e-36: 132: 26.47
+	Hs
		243360 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		DNJA2_HUMAN (36-96): 8.35e-09: 57: 47.54
+	Hs
		411615 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		DNJA1_HUMAN (31-99): 2.12e-29: 115: 37.68
+	Hs
		412302 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		DNJA3_HUMAN (3-191): 5.67e-43: 153: 21.69
+	Hs
		681357 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		DNJA1_HUMAN (31-99): 2.12e-29: 115: 37.68
+	Hs
		681442 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		DNJA1_HUMAN (31-99): 2.12e-29: 115: 37.68
+	Hs
		855802 VAV2_HUMAN (3-56): 4.83e-11: 63.5: 38.18		DJC21_HUMAN (35-238): 1.03e-39: 145: 17.06
+	Hs
		1078924 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		DJB11_HUMAN (33-134): 3.08e-36: 132: 26.47
+	Hs
		243255 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		DNJA2_HUMAN (36-96): 8.35e-09: 57: 47.54
+	Hs
		548651 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		DNJA1_HUMAN (31-99): 2.12e-29: 115: 37.68
+	Hs
		433497 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		DNJ5B_HUMAN (28-103): 5.22e-31: 115: 34.18
+	Hs
		243401 PTK6_HUMAN (4-141): 7.14e-23: 97.1: 38.93		DNJA2_HUMAN (36-96): 8.35e-09: 57: 47.54
+	Hs
		243282 VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37		DNJA2_HUMAN (36-96): 8.35e-09: 57: 47.54
+	Hs
		243421 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		DNJA2_HUMAN (36-96): 8.35e-09: 57: 47.54