Protein: NOP14
Nucleolar protein 14 (Nucleolar complex protein 14)

Gene: NOP14
Organism: Homo sapiens
Interactions: 199
UniProt ID: P78316

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1004335

BYST
Bystin

5

1

High-throughput

0.718

High

1004325

H11
Histone H1.1

3

2

High-throughput

0.667

High

1004360

STX12
Syntaxin-12

3

1

High-throughput

0.667

High

371728

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.640

High

134006

IPO5
Importin-5

3

0

High-throughput

0.638

High

521640

H14
Histone H1.4

2

2

High-throughput

0.628

High

323863

SC31A
Protein transport protein Sec31A

3

1

High-throughput

0.616

High

984708

RL31
Large ribosomal subunit protein eL31

2

1

High-throughput

0.611

High

1004379

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

2

1

High-throughput

0.611

High

189504

STX7
Syntaxin-7

3

1

High-throughput

0.609

High

969787

RS16
Small ribosomal subunit protein uS9

2

0

High-throughput

0.602

High

809587

RS19
Small ribosomal subunit protein eS19

2

1

High-throughput

0.601

High

1004334

KRR1
KRR1 small subunit processome component homolog

2

1

High-throughput

0.601

High

1004430

YBOX2
Y-box-binding protein 2

2

1

High-throughput

0.601

High

1004412

SLX9
Ribosome biogenesis protein SLX9 homolog

2

0

Small-scale

0.585

High

96658

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

643774

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

High-throughput

0.584

High

1004322

H33
Histone H3.3

2

3

High-throughput

0.584

High

407609

S100B
Protein S100-B

2

0

High-throughput

0.576

High

601621

HMGA1
High mobility group protein HMG-I/HMG-Y

2

0

High-throughput

0.576

High

1004418

DAXX
Death domain-associated protein 6

2

0

High-throughput

0.576

High

1004422

PURG
Purine-rich element-binding protein gamma

2

0

High-throughput

0.576

High

395877

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

128955

MEN1
Menin

2

0

High-throughput

0.559

High

978849

RS6
Small ribosomal subunit protein eS6

2

0

High-throughput

0.559

High

1004409

ANLN
Anillin

2

0

High-throughput

0.559

High

208229

RRP8
Ribosomal RNA-processing protein 8

1

1

High-throughput

0.536

High

224890

BUD23
18S rRNA

1

1

High-throughput

0.536

High

301005

RL1D1
Ribosomal L1 domain-containing protein 1

1

2

High-throughput

0.536

High

338805

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.536

High

959730

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.536

High

972359

RS14
Small ribosomal subunit protein uS11

1

1

High-throughput

0.536

High

973391

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

1004346

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

2

High-throughput

0.536

High

1004348

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.536

High

1004363

DHX37
Probable ATP-dependent RNA helicase DHX37

1

2

High-throughput

0.536

High

1004397

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.536

High

1004407

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.536

High

1004432

RBM19
Probable RNA-binding protein 19

1

1

High-throughput

0.536

High

462343

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.515

High

290520

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

502308

H2A1
Histone H2A type 1

1

0

High-throughput

0.513

High

634402

LMNB1
Lamin-B1

1

0

High-throughput

0.513

High

884059

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

884998

DGKG
Diacylglycerol kinase gamma

1

0

High-throughput

0.513

High

973134

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.513

High

978468

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

1004326

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.513

High

1004330

MALL
MAL-like protein

1

0

High-throughput

0.513

High

1004333

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.513

High

1004343

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

1004344

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.513

High

1004345

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.513

High

1004385

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.513

High

1004423

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

339716

KLF8
Krueppel-like factor 8

1

2

High-throughput

0.500

High

1004421

KLF15
Krueppel-like factor 15

1

2

High-throughput

0.500

High

1004401

FOXQ1
Forkhead box protein Q1

1

1

High-throughput

0.489

High

776171

SOX6
Transcription factor SOX-6

1

0

High-throughput

0.479

High

140573

MPP10
U3 small nucleolar ribonucleoprotein protein MPP10

1

1

High-throughput

0.479

High

140864

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

254348

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.479

High

256828

H2B1K
Histone H2B type 1-K

1

4

High-throughput

0.479

High

262511

MCE1
mRNA-capping enzyme

1

1

High-throughput

0.479

High

406039

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

487184

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

765371

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

789468

PPARG
Peroxisome proliferator-activated receptor gamma

1

2

Small-scale

0.479

High

883499

CENPA
Histone H3-like centromeric protein A

1

3

High-throughput

0.479

High

946748

H2B1D
Histone H2B type 1-D

1

4

High-throughput

0.479

High

980686

H2B1C
Histone H2B type 1-C/E/F/G/I

1

4

High-throughput

0.479

High

982616

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

998193

H31
Histone H3.1

1

3

High-throughput

0.479

High

1004323

EXOSX
Exosome complex component 10

1

1

High-throughput

0.479

High

1004332

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.479

High

1004361

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.479

High

1004366

H2B3B
Histone H2B type 3-B

1

4

High-throughput

0.479

High

1004369

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1004376

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1004377

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.479

High

1004380

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

3

High-throughput

0.479

High

1004382

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

1004383

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

Small-scale

0.479

High

1004384

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.479

High

1004390

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.479

High

1004391

H2B1L
Histone H2B type 1-L

1

4

High-throughput

0.479

High

1004396

NOC4L
Nucleolar complex protein 4 homolog

1

2

High-throughput

0.479

High

1004400

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

1

High-throughput

0.479

High

1004402

DDX24
ATP-dependent RNA helicase DDX24

1

3

High-throughput

0.479

High

1004410

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.479

High

1004411

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

1004413

NLE1
Notchless protein homolog 1

1

1

High-throughput

0.479

High

1004414

AATF
Protein AATF

1

1

High-throughput

0.479

High

1004426

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

1004429

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

1

High-throughput

0.479

High

157225

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

190873

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

241368

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

259777

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

319657

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

324773

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

345656

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

446892

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

472625

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

588447

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

657530

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

695187

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

697067

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

702927

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

766437

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

767940

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

799843

COIL
Coilin

1

0

High-throughput

0.458

High

807365

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

832507

ETV3
ETS translocation variant 3

1

0

High-throughput

0.458

High

878947

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

904579

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

994980

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1004319

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1004324

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1004327

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1004328

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1004329

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.458

High

1004331

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.458

High

1004340

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1004341

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1004342

ZMY11
Zinc finger MYND domain-containing protein 11

1

0

Small-scale

0.458

High

1004353

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.458

High

1004359

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1004365

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1004367

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1004370

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1004372

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1004374

DNJC9
DnaJ homolog subfamily C member 9

1

0

High-throughput

0.458

High

1004381

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1004386

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1004388

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1004389

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.458

High

1004395

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1004399

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1004403

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1004416

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1004417

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1004419

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1004431

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1004398

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.457

High

967392

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.445

High

977194

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.445

High

1004338

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.445

High

1004347

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

1004393

UTP23
rRNA-processing protein UTP23 homolog

1

1

High-throughput

0.445

High

1004415

H2AW
Core histone macro-H2A.2

1

1

High-throughput

0.445

High

1004425

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.445

High

504879

H2AB2
Histone H2A-Bbd type 2/3

1

1

High-throughput

0.437

High

505646

DC8L2
DDB1- and CUL4-associated factor 8-like protein 2

1

2

Small-scale

0.437

High

1004405

TXNIP
Thioredoxin-interacting protein

1

4

Small-scale

0.437

High

615729

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.426

High

810037

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

860703

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.426

High

1004320

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.426

High

1004321

PRR3
Proline-rich protein 3

1

0

High-throughput

0.426

High

1004336

SLBP
Histone RNA hairpin-binding protein

1

0

High-throughput

0.426

High

1004339

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1004350

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1004364

YAF2
YY1-associated factor 2

1

0

High-throughput

0.426

High

1004368

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

1004371

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

0

High-throughput

0.426

High

1004378

EDA
Ectodysplasin-A

1

0

High-throughput

0.426

High

1004392

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

1004394

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.426

High

1004404

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

1004408

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

1004427

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.426

High

69935

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

649294

H1T
Histone H1t

1

2

High-throughput

0.407

High

1004351

L2GL2
LLGL scribble cell polarity complex component 2

1

1

High-throughput

0.407

High

886736

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1004349

Z324B
Zinc finger protein 324B

2

0

High-throughput

0.328

High

1004387

ZN414
Zinc finger protein 414

2

0

High-throughput

0.328

High

221933

FOXS1
Forkhead box protein S1

1

0

High-throughput

0.279

Low

596469

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

976196

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.279

Low

1004337

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1004355

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

1004357

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

1004362

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.279

Low

1004428

STX8
Syntaxin-8

1

0

High-throughput

0.279

Low

317824

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.249

Low

571412

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

970310

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1004352

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1004354

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

1004356

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1004375

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.249

Low

1004406

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1004424

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

47512

RPSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low

1004358

LRRT3
Leucine-rich repeat transmembrane neuronal protein 3

1

0

High-throughput

0.232

Low

1004373

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.232

Low

1004420

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025